Monitoring the Right Collection: The Central Cholinergic Neurons as an Instructive Example

Frontiers in Neural Circuits
Katalin Sviatkó, Balázs Hangya

Abstract

Some neurons are more equal than others: neuroscience relies heavily on the notion that there is a division of labor among different subtypes of brain cells. Therefore, it is important to recognize groups of neurons that participate in the same computation or share similar tasks. However, what the best ways are to identify such collections is not yet clear. Here, we argue that monitoring the activity of genetically defined cell types will lead to new insights about neural mechanisms and improve our understanding of disease vulnerability. Through highlighting how central cholinergic neurons encode reward and punishment that can be captured by a unified framework of reinforcement surprise, we hope to provide an instructive example of how studying a genetically defined cell type may further our understanding of neural function.

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Citations

Jul 29, 2018·The European Journal of Neuroscience·Nicola Solari, Balázs Hangya
Jun 9, 2020·Frontiers in Neuroinformatics·András SzéllBalázs Hangya

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BETA
biosensors

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