Monitoring vaccine safety using case series cumulative sum charts.

Vaccine
Patrick MusondaC Paddy Farrington

Abstract

We adapt the self-controlled case series method for routine surveillance of vaccine safety using cumulative sum (CUSUM) charts. The CUSUM surveillance method we propose is applicable for detecting associations that arise in a short pre-determined risk period following vaccination. The performance of the case series CUSUM is investigated through simulations. We illustrate the method using retrospective analyses of influenza vaccine and Bell's palsy, and MMR vaccine and febrile convulsions.

References

May 1, 1994·Vaccine·R T ChenS G Wassilak
Jun 1, 1996·American Journal of Epidemiology·C P FarringtonE Miller
Oct 16, 2003·Pharmacoepidemiology and Drug Safety·A Lawrence Gould
Oct 13, 2005·Statistics in Medicine·Heather J WhitakerPatrick Musonda
Dec 29, 2005·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Emmanuel RouxPascale Tubert-Bitter
Oct 3, 2006·Human Vaccines·Julia StoweElizabeth Miller

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Citations

Nov 26, 2010·Revue D'épidémiologie Et De Santé Publique·M N Hocine, M Chavance
Oct 17, 2012·Statistical Methods in Medical Research·Pascale Tubert-BitterIsmaïl Ahmed
Jul 4, 2012·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Liangyou ChenJaques Reifman

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