Monkey V1 epidural field potentials provide detailed information about stimulus location, size, shape, and color.

Communications Biology
Benjamin Fischer, Detlef Wegener

Abstract

Brain signal recordings with epidural microarrays constitute a low-invasive approach for recording distributed neuronal signals. Epidural field potentials (EFPs) may serve as a safe and highly beneficial signal source for a variety of research questions arising from both basic and applied neuroscience. A wider use of these signals, however, is constrained by a lack of data on their specific information content. Here, we make use of the high spatial resolution and the columnar organization of macaque primary visual cortex (V1) to investigate whether and to what extent EFP signals preserve information about various visual stimulus features. Two monkeys were presented with different feature combinations of location, size, shape, and color, yielding a total of 375 stimulus conditions. Visual features were chosen to access different spatial levels of functional organization. We found that, besides being highly specific for locational information, EFPs were significantly modulated by small differences in size, shape, and color, allowing for high stimulus classification rates even at the single-trial level. The results support the notion that EFPs constitute a low-invasive, highly beneficial signal source for longer-term recordings fo...Continue Reading

References

Jun 1, 1980·Brain : a Journal of Neurology·A J RockelT P Powell
May 3, 2000·The European Journal of Neuroscience·A HanazawaI Murakami
Dec 22, 2004·Nature Reviews. Neuroscience·Andreas K EngelGeorge A Ojemann
Dec 19, 2006·Cerebral Cortex·Daniel YoshorJohn H R Maunsell
Feb 6, 2007·NeuroImage·Youping XiaoEhud Kaplan
Dec 28, 2007·Journal of Neurophysiology·Malte J RaschNikos K Logothetis
Nov 7, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Supratim RaySteven S Hsiao
Mar 7, 2009·NeuroImage·Tonio BallAndreas Schulze-Bonhage
Apr 30, 2009·Annual Review of Neuroscience·Pascal Fries
Jan 30, 2010·Journal of Neuroscience Methods·Aldemar Torres ValderramaNicolas Franciscus Ramsey
Nov 12, 2010·Journal of Neurophysiology·Theodoros P ZanosChristopher C Pack
Apr 22, 2011·Journal of Neural Engineering·Marc W SlutzkyLee E Miller
May 3, 2011·PLoS Biology·Supratim Ray, John H R Maunsell
Jun 24, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Xiaoxuan JiaAdam Kohn
Sep 20, 2011·Journal of Neuroscience Methods·Agnieszka Grabska-BarwińskaDirk Jancke
Dec 14, 2011·Neuron·Henrik LindénGaute T Einevoll
Apr 28, 2012·Journal of Neurophysiology·Jorge J RieraRyuta Kawashima
May 19, 2012·Nature Reviews. Neuroscience·György BuzsákiChristof Koch
Mar 2, 2013·Frontiers in Neural Circuits·Nicole A YoungJon H Kaas
Mar 22, 2014·Journal of Neural Engineering·David T BundyEric C Leuthardt
Dec 30, 2014·Current Opinion in Neurobiology·C M LewisP Fries
Sep 1, 2017·ELife·Eric LowetPeter De Weerd
Feb 15, 2018·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Dinavahi V P S MurtySupratim Ray
Mar 7, 2018·Nature Neuroscience·Josef Parvizi, Sabine Kastner
Apr 11, 2018·Proceedings of the National Academy of Sciences of the United States of America·Vinay Shirhatti, Supratim Ray
Feb 28, 2019·Frontiers in Neuroscience·Eric DrebitzDetlef Wegener
Mar 28, 2019·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Agrita Dubey, Supratim Ray
Aug 15, 2019·Journal of Neurophysiology·Benjamin FischerDetlef Wegener
Oct 8, 2019·Current Biology : CB·Eleonora BartoliBrett L Foster

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