Mono- and Bimetallic Aluminum Alkyl, Alkoxide, Halide and Hydride Complexes of a Bulky Conjugated Bis-Guanidinate(CBG) Ligand and Aluminum Alkyls as Precatalysts for Carbonyl Hydroboration

Inorganic Chemistry
Thota PeddaraoSharanappa Nembenna

Abstract

Tetra-aryl-substituted symmetrical conjugated bis-guanidine (CBG) ligands such as L1-3 (3H) [L(3H) = {(ArHN)(ArHN)C═N-C═NAr(NHAr)}; Ar = 2,6-Me2-C6H3 (L1(3H)), 2,6-Et2-C6H3 (L2(3H)), and 2,6- i Pr2-C6H3 (L3(3H))] have been employed to synthesize a series of four- and six-membered aluminum heterocycles (1-8) for the first time. Generally, aluminum complexes bearing N,N'- chelated guanidinate and β-diketiminate/dipyrromethene ligand systems form four- and six-membered heterocycles, respectively. However, the conjugated bis-guanidine ligand has the capability of forming both four- and six-membered heterocycles possessing multimetal centers within the same molecule; this is due to the presence of three acidic protons, which can be easily deprotonated (at least two protons) upon treatment with metal reagents. Both mono- and dinuclear aluminum alkyls and mononuclear aluminum alkoxide, halide, and hydride complexes have been structurally characterized. Further, we have demonstrated the potential of mononuclear, six-membered CBG aluminum dialkyls in catalytic hydroboration of a broad range of aldehydes and ketones with pinacolborane (HBpin).

References

Oct 24, 2001·The Journal of Organic Chemistry·Hugo E. GottliebAbraham Nudelman
Sep 12, 2002·Chemical Reviews·Laurence Bourget-MerleJohn R Severn
Feb 14, 2006·Dalton Transactions : an International Journal of Inorganic Chemistry·Martyn P Coles
Dec 25, 2007·Acta Crystallographica. Section A, Foundations of Crystallography·George M Sheldrick
Jun 19, 2008·Dalton Transactions : an International Journal of Inorganic Chemistry·Shaogang Gong, Haiyan Ma
Sep 24, 2010·Nature Chemistry·Simon J BonyhadyAndreas Stasch
Jan 21, 2011·Accounts of Chemical Research·Sankaranarayana Pillai SarishHerbert W Roesky
Mar 11, 2011·Dalton Transactions : an International Journal of Inorganic Chemistry·Andreas Stasch, Cameron Jones
May 4, 2013·Science·Elisabeth T Hennessy, Theodore A Betley
Dec 30, 2014·Acta Crystallographica. Section A, Foundations and Advances·George M Sheldrick
Jan 9, 2015·Acta Crystallographica. Section C, Structural Chemistry·George M Sheldrick
Jun 20, 2015·Angewandte Chemie·Zhi YangHerbert W Roesky
Jun 23, 2015·Accounts of Chemical Research·Sumit ChakrabortyHairong Guan
Aug 6, 2015·Dalton Transactions : an International Journal of Inorganic Chemistry·Chi ChenPatrick L Holland
Feb 16, 2016·Dalton Transactions : an International Journal of Inorganic Chemistry·Naveen V KulkarniH V Rasika Dias
Jun 30, 2016·Dalton Transactions : an International Journal of Inorganic Chemistry·Clément Camp, John Arnold
Aug 4, 2016·Dalton Transactions : an International Journal of Inorganic Chemistry·Christopher G GianopoulosMark R Mason
Mar 7, 2017·Dalton Transactions : an International Journal of Inorganic Chemistry·R L Webster
Jun 14, 2017·Dalton Transactions : an International Journal of Inorganic Chemistry·Bei-Bei GuoGuo-Xin Jin
Oct 1, 2015·Chemical Science·Olga EkkertMark R Crimmin
Aug 5, 2017·Journal of the American Chemical Society·Matthew J T WildingTheodore A Betley
Sep 5, 2017·Chemical Communications : Chem Comm·Diana A IovanTheodore A Betley
Jan 18, 2018·Chemical Communications : Chem Comm·Victoria A PollardRobert E Mulvey
Feb 17, 2018·Chemistry : a European Journal·Billa PrashanthSanjay Singh
Mar 9, 2019·Dalton Transactions : an International Journal of Inorganic Chemistry·Alexa CaiseSimon Aldridge
Apr 30, 2019·Organic & Biomolecular Chemistry·Xi-Yang CuiDasheng Leow
May 24, 2019·Dalton Transactions : an International Journal of Inorganic Chemistry·Javier Francos, Victorio Cadierno
Nov 9, 2019·Journal of the American Chemical Society·Yury LebedevMagnus Rueping
Jan 3, 2020·ChemCatChem·Daniel FranzShigeyoshi Inoue

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.