Monoaminergic signaling as a target for anthelmintic drug discovery: receptor conservation among the free-living and parasitic nematodes.

Molecular and Biochemical Parasitology
Richard KomunieckiRobin B Gasser

Abstract

This review is designed to summarize the information on monoamine-dependent paralysis as a target for anthelmintic development, examine the conservation of monoamine receptors in the genomes of both free-living and parasitic nematodes, and highlight the utility of the Caenorhabditis elegans model system for dissecting the monoaminergic modulation of locomotory decision-making.

References

May 28, 1982·Science·H R HorvitzP D Evans
Oct 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·J A NathansonC Scavone
May 1, 1996·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·C A Reinitz, A O Stretton
Nov 27, 1998·British Medical Bulletin·D A Bundy, N R de Silva
May 14, 1999·Parasitology Today·N C Sangster, J Gill
Mar 16, 2000·Proceedings of the National Academy of Sciences of the United States of America·J A DentL Avery
Nov 15, 2001·Veterinary Parasitology·T G Geary, D P Thompson
Oct 2, 2002·Journal of Neurochemistry·Elizabeth Rex, Richard W Komuniecki
Sep 19, 2003·International Journal of Antimicrobial Agents·Achim HarderRobert Walker
Sep 21, 2004·Nature Neuroscience·Daniel L ChaseMichael R Koelle
Jun 1, 2005·Trends in Parasitology·John S GilleardJulian A T Dow
Jun 15, 2005·Journal of Neurochemistry·Elizabeth RexRichard Komuniecki
Sep 22, 2007·Science·Elodie GhedinAlan L Scott
Nov 21, 2007·Invertebrate Neuroscience : in·Katherine A SmithJohn Gray
Dec 1, 2007·WormBook : the Online Review of C. Elegans Biology·Daniel L Chase, Michael R Koelle
Apr 3, 2008·The Journal of Clinical Investigation·Peter J HotezJulie Jacobson
Nov 21, 2008·Proceedings of the National Academy of Sciences of the United States of America·Thomas BoulinJean-Louis Bessereau
Nov 10, 2009·Nature Methods·Zengcai V GuoSharad Ramanathan
Apr 20, 2010·Nature Neuroscience·Roger Pocock, Oliver Hobert
May 18, 2010·Molecular and Biochemical Parasitology·Vijayaraghava T S RaoSean G Forrester
Jun 17, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Gholamali JafariJi Ying Sze
Oct 5, 2011·Nature Reviews. Genetics·Xiao Xu, Stuart K Kim

❮ Previous
Next ❯

Citations

Aug 30, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Vera HapiakRichard Komuniecki
Nov 18, 2015·Bioorganic & Medicinal Chemistry Letters·Daniel GlobischKim D Janda
Oct 6, 2018·The Journal of Experimental Biology·Ann Jane Tierney
Sep 26, 2020·Frontiers in Neuroscience·María Julia CastroCecilia Bouzat

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.