Abstract
The innate immune response is generally considered to have an important role in tissue remodeling after resistance exercise. The purpose of this study was to compare changes in markers of monocyte recruitment after an acute bout of high-intensity (HVY) versus high-volume (VOL) lower-body resistance exercise. Ten resistance-trained men (24.7 ± 3.4 yr, 90.1 ± 11.3 kg, 176.0 ± 4.9 cm) performed each protocol in a randomized, counterbalanced order. Blood samples were collected at baseline, immediately (IP), 30 min (30P), 1 h (1H), 2 h (2H), and 5 h (5H) postexercise. Plasma concentrations of monocyte chemoattractant protein 1 (MCP-1), tumor necrosis factor alpha (TNF-α), myoglobin, and cortisol were measured via assay. Tumor necrosis factor receptor 1 (TNFr1), macrophage-1 antigen (cluster of differentiation 11b [CD11b]), and C-C chemokine receptor 2 (CCR2) expression levels were measured using flow cytometry. TNFr1 and CD11b were assessed on CD14CD16 monocytes, whereas CCR2 was assessed on CD14 monocytes. Plasma myoglobin concentrations were significantly greater after HVY compared with VOL (P < 0.001). Changes in plasma TNF-α, MCP-1, and expression levels of CCR2 and CD11b were similar between HVY and VOL. When collapsed across g...Continue Reading
References
Aug 1, 1974·Journal of Applied Physiology·D B Dill, D L Costill
Nov 22, 1997·European Journal of Immunology·J J CampbellE C Butcher
Jan 22, 1998·Proceedings of the National Academy of Sciences of the United States of America·M GrellP Scheurich
Apr 3, 1999·Medicine and Science in Sports and Exercise·J JordanH Haller
Sep 29, 1999·European Journal of Applied Physiology and Occupational Physiology·I K BrennerR J Shephard
Jul 6, 2000·European Journal of Applied Physiology·L L SmithD Holbert
Aug 16, 2000·American Journal of Physiology. Cell Physiology·B SteppichH W Ziegler-Heitbrock
Oct 12, 2000·Biochemical and Biophysical Research Communications·K MuraoJ Takahara
Sep 18, 2003·The Journal of Biological Chemistry·Kazuhiko TakahashiHidehito Kotani
Dec 10, 2003·The Journal of Cell Biology·Bénédicte ChazaudRomain K Gherardi
Mar 23, 2004·Annual Review of Immunology·Antal Rot, Ulrich H von Andrian
Nov 16, 2005·Medicine and Science in Sports and Exercise·Gøran PaulsenTruls Raastad
Feb 21, 2006·The Journal of Surgical Research·Paula K ShiremanLinda M McManus
Dec 1, 2006·Journal of Leukocyte Biology·Paula K ShiremanLinda M McManus
May 9, 2007·The Journal of Experimental Medicine·Ludovic ArnoldBénédicte Chazaud
Aug 25, 2007·Nature Reviews. Immunology·Klaus LeySussan Nourshargh
Dec 7, 2007·British Journal of Pharmacology·E KellyG Henderson
Feb 5, 2008·Brain, Behavior, and Immunity·Suzi Hong, Paul J Mills
May 15, 2008·Brain, Behavior, and Immunity·Mitsuharu OkutsuMitsuru Higuchi
Jul 30, 2008·Journal of Leukocyte Biology·Tracy M HandelAmanda E I Proudfoot
Nov 3, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Ronen SumaginIngrid H Sarelius
Nov 20, 2010·Molecular Pharmacology·Yamina A BerchicheNikolaus Heveker
Jan 29, 2011·The Journal of Experimental Biology·Kyle L FlannStan L Lindstedt
Jun 10, 2011·Blood·Kok Loon WongSiew-Cheng Wong
Oct 8, 2011·Immunology·Laura D BennettNathalie Signoret
Mar 21, 2012·Immunologic Research·Kok Loon WongSiew Cheng Wong
May 23, 2012·PloS One·Silvia VolpeMarcus Thelen
Oct 9, 2012·Journal of Inflammation·Daniëlle HijdraGer T Rijkers
Feb 12, 2013·Cell Metabolism·Brendan Egan, Juleen R Zierath
Jul 6, 2014·Mediators of Inflammation·Adam R JajtnerJay R Hoffman
Aug 26, 2014·European Journal of Applied Physiology·Johanna IhalainenAntti A Mero
Oct 15, 2014·PloS One·Leeann M BellamyGianni Parise
Mar 6, 2015·Frontiers in Physiology·Jeremy R TownsendJeffrey R Stout
Citations
Jul 8, 2016·Nutrients·Adam J WellsJeffrey R Stout
Mar 21, 2017·Medicine and Science in Sports and Exercise·Julianne C BarryJonathan P Little
Jun 30, 2018·Medicine and Science in Sports and Exercise·Adam R JajtnerJay R Hoffman
Oct 21, 2017·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Johanna K IhalainenAntti A Mero
Nov 30, 2019·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Igor Martins da SilvaAlessandra Peres
May 31, 2017·Amino Acids·Adam J WellsJay R Hoffman
Apr 28, 2017·European Journal of Applied Physiology·Sandro BartolomeiJay R Hoffman
Sep 19, 2020·Journal of Strength and Conditioning Research·Adam J WellsJay R Hoffman
Oct 27, 2020·Journal of Strength and Conditioning Research·Adam J WellsJay R Hoffman