PMID: 6397199Dec 1, 1984Paper
Monocytic origin of foam cells in human atherosclerotic plaques
Atherosclerosis
N M AqelM J Mitchinson
Abstract
Foam cells in 4 human atherosclerotic plaques reacted with 3 rat monoclonal antibodies directed against T.200 ('anti-leucocyte common' antibody), HLA-Class II molecules and macrophage cytoplasm, respectively. Smooth muscle cells did not react. The results support the view that foam cells are monocyte-derived macrophages.
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