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Monogenic lupus: Dissecting heterogeneity

Autoimmunity Reviews

Oct 8, 2019

Ommar OmarjeeAlexandre Belot

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Abstract

Systemic lupus erythematosus (SLE) is a severe lifelong multisystem autoimmune disease characterized by the presence of autoantibodies targeting nuclear autoantigens, increased production of type I interferon and B cell abnormalities. Clinical presentation of SLE is extremely heterogene...read more

Mentioned in this Paper

Autoantibodies
Autoimmune Diseases
B-Lymphocytes
Genes
Immune Tolerance
Interferons
Literature
Lupus Erythematosus, Systemic
Lymphoproliferative Disorders
Metabolism
7
1
11
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Monogenic lupus: Dissecting heterogeneity

Autoimmunity Reviews

Oct 8, 2019

Ommar OmarjeeAlexandre Belot

PMID: 31401343

DOI: 10.1016/j.autrev.2019.102361

Abstract

Systemic lupus erythematosus (SLE) is a severe lifelong multisystem autoimmune disease characterized by the presence of autoantibodies targeting nuclear autoantigens, increased production of type I interferon and B cell abnormalities. Clinical presentation of SLE is extremely heterogene...read more

Mentioned in this Paper

Autoantibodies
Autoimmune Diseases
B-Lymphocytes
Genes
Immune Tolerance
7
1
11

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