PMID: 9178279Apr 1, 1997Paper

Mononuclear blood cell magnesium content and serum magnesium concentration in critically ill hypomagnesemic patients after replacement therapy

Nutrition
G S SacksK A Kudsk

Abstract

Magnesium (Mg) deficiency, commonly diagnosed as hypomagnesemia based upon low serum Mg concentrations, is a frequent electrolyte abnormality in critically ill patients. Intravenous replacement therapy is empiric and serum Mg concentrations have traditionally been used as guidelines for measuring efficacy. Recent studies have shown that the Mg content of mononuclear blood cells (MBCs) may provide a better index for Mg status than serum concentrations. The purpose of this study was to evaluate the effects of intravenous Mg replacement therapy on MBC Mg content and serum Mg concentrations in critically ill hypomagnesemic patients. Adult patients admitted to the trauma intensive-care unit (ICU) with serum Mg concentration < or = 0.6 mmol/L (< or = 1.5 mg/dL) were considered for study entry. Patients with severe renal disease (Scr > 133 mumol/L), pregnancy, or those who were seropositive for HIV were excluded. Ten patients with moderate (> 0.4-0.6 mmol/L [> 1.0-1.5 mg/dL]) and severe (< or = 0.4 mmol/L [< or = 1.0 mg/dL]) hypomagnesemia received 0.5 and 0.75 mmol/kg of intravenous MgSO4, respectively, over 24 h. MBC Mg content and serum concentrations of magnesium, phosphorus, calcium, sodium, potassium, blood urea nitrogen, creati...Continue Reading

References

Jun 1, 1975·The American Journal of Medicine·L T IseriA R Bures
Feb 1, 1989·Chest·B ChernowA L Warshaw
Aug 1, 1988·Critical Care Medicine·E FiaccadoriA Borghetti
Mar 20, 1987·The American Journal of Medicine·R Whang
Jan 1, 1985·Critical Care Medicine·E RyzenR K Rude
Jun 1, 1985·Critical Care Medicine·R A Reinhart, N A Desbiens
Aug 18, 1972·Science·C S AnastT W Burns
Aug 15, 1969·Annals of the New York Academy of Sciences·E B Flink
Jan 29, 1983·British Medical Journal·J P Sheehan
Jan 1, 1983·Journal of the American College of Nutrition·J M HosseiniR J Elin
Mar 1, 1982·The American Journal of Medicine·Z S AgusS Goldfarb
Mar 1, 1982·The American Journal of Medicine·J P Knochel
Dec 1, 1980·The Journal of Clinical Endocrinology and Metabolism·R K RudeF R Singer
Jun 17, 1994·Annals of the New York Academy of Sciences·W B WeglickiJ H Kramer
Feb 1, 1993·Critical Care Medicine·G J RubeizR W Carlson
Dec 15, 2010·Clinical Oral Implants Research·Marina Montosa BelluciSilvana Regina Perez Orrico

❮ Previous
Next ❯

Citations

Dec 3, 2010·The Journal of Nutrition, Health & Aging·Z UlgerO Akyol
Sep 5, 2015·Journal of Critical Care·Jessica FairleyRinaldo Bellomo
Aug 10, 2007·Intensive & Critical Care Nursing : the Official Journal of the British Association of Critical Care Nurses·Phillip OwenRobert MacLaren
Apr 28, 2007·JPEN. Journal of Parenteral and Enteral Nutrition·Roland N DickersonRex O Brown
Nov 25, 2005·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Michael D KraftGordon S Sacks
Feb 8, 2007·Proceedings. Biological Sciences·John J WiensDavid B Wake

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

JPEN. Journal of Parenteral and Enteral Nutrition
Roland N Dickerson
Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition
Carol RollinsASPEN Task Force for Revision of Nutrition Support Pharmacist Standards
Critical Care Clinics
Joseph Dooley, Allison Fegley
© 2021 Meta ULC. All rights reserved