Monopolar Radiofrequency Ablation of Thyroid Nodules: A Prospective Austrian Single-Center Study

Thyroid : Official Journal of the American Thyroid Association
Harald Dobnig, Karin Amrein

Abstract

Monopolar radiofrequency ablation is currently deemed an exotic treatment option for benign thyroid nodules in many central European countries. The aim of this study was to evaluate prospectively the safety and efficacy of this method in a large patient cohort following its introduction in Austria. Peri- and post-interventional complications were analyzed for 277 patients. Efficacy was determined for 300 and 154 nodules at 3 and 12 months post treatment, respectively. All treatments were performed with an internally cooled 18G radiofrequency electrode using a free-hand, "moving-shot" technique following subcutaneous and local perithyroidal anesthesia. Mean patient age (SD) was 52 ± 12.9 years (75% female), and overall mean baseline nodule volume (SD) was 13.8 ± 15.9 mL. Nodules were visible in 62.8% of patients, 40% had a symptom score ≥4 on a 10-point visual analogue scale, and 14.4% had hyperthyroidism. Mean overall nodule volume reduction rates (VRR) at 3 and 12 months were 68 ± 16% and 82 ± 13%, respectively (p < 0.001). At 12 months, 81% of nodules exhibited a VRR of ≥70%, with 10%, 6%, and 2% of nodules showing VRRs of 60-70%, 50-60%, and ≤50%, respectively. Subgroup analysis according to baseline nodule size (≤10 mL to >...Continue Reading

Associated Clinical Trials

References

May 2, 2006·Thyroid : Official Journal of the American Thyroid Association·Young-Sun KimSung Tae Kim
Mar 7, 2009·Thyroid : Official Journal of the American Thyroid Association·Stefano SpieziaAntongiulio Faggiano
Jul 4, 2009·World Journal of Surgery·Jung Hwan BaekDucky Lee
Mar 23, 2012·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Dong Gyu NaUNKNOWN Korean Society of Radiology
Sep 28, 2012·Thyroid : Official Journal of the American Thyroid Association·Eun Ju HaYoung Kee Shong
May 3, 2014·Ultrasound in Medicine & Biology·Giovanni TurtuliciJung Hwan Baek
Jul 22, 2014·International Journal of Endocrinology·Stella BernardiFulvio Stacul
Oct 17, 2014·Thyroid : Official Journal of the American Thyroid Association·Jin Yong SungDong Gyu Na
Dec 3, 2014·World Journal of Surgery·M Umit UgurluBahadir M Gulluoglu
Mar 4, 2015·JAMA : the Journal of the American Medical Association·Cosimo DuranteSebastiano Filetti
Mar 31, 2015·AJNR. American Journal of Neuroradiology·Y CheJ H Baek
Jun 30, 2015·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Roberto Valcavi, Petros Tsamatropoulos
Aug 13, 2015·International Journal of Endocrinology·Chiara DobrinjaFulvio Stacul
Apr 22, 2016·Journal of Endocrinological Investigation·S BernardiB Fabris
Jul 19, 2017·Clinical Endocrinology·Roberto CesareoClaudio Maurizio Pacella

❮ Previous
Next ❯

Citations

Dec 11, 2019·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Huaxiang YangJing Yan
Oct 28, 2019·Journal of Endocrinological Investigation·C CappelliM Castellano
Feb 27, 2020·World Journal of Surgery·Huynh Quang KhanhNguyen Lam Vuong
Jul 20, 2019·Molecular Medicine Reports·Felician StancioiuCorin Badiu
Mar 20, 2019·Reviews in Endocrine & Metabolic Disorders·Roberto CesareoPierpaolo Trimboli
Mar 4, 2020·MMW Fortschritte der Medizin·Angelika Bischoff
Jun 6, 2019·World Journal of Surgery·Nguyen Lam VuongTran Thanh Vy
Jan 8, 2020·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·Joachim FeldkampDagmar Führer
Jan 16, 2021·Endocrine·Haris MuhammadJonathon O Russell
Jan 26, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Gilles RussCamille Buffet
Nov 17, 2020·Frontiers in Oncology·Xiao-Wan BoKun Zhang
Feb 23, 2021·Laryngoscope Investigative Otolaryngology·Haris MuhammadJennifer H Kuo
Apr 16, 2021·Annals of the Academy of Medicine, Singapore·Elvin Y T LimChow Wei Too
May 29, 2021·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jung Suk Sim, Jung Hwan Baek
Jul 16, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Nana WangJie Ren
Aug 17, 2021·Technology and Health Care : Official Journal of the European Society for Engineering and Medicine·Robert M EiseleGereon Gäbelein
Oct 9, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Qian-Qian FuShuang-Quan Jiang
Dec 26, 2021·The Journal of Clinical Endocrinology and Metabolism·Marius N StanM Regina Castro

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
sedation

Software Mentioned

SPSS Statistics

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.