Monster protein controls calcium entry and fights infection

Immunity
Amy N Radermacher, Gerald R Crabtree

Abstract

Sustained calcium signaling in T cells is critical for development and activation. In this issue of Immunity, Matza et al. (2007) demonstrate that the huge scaffold protein, AHNAK1, interacts with L-type calcium channels, regulates Ca2+ influx, and defends against Leishmania major infection.

References

Sep 1, 1987·Annales De L'Institut Pasteur. Immunology·R M LocksleyK D Gardner
May 12, 2007·Trends in Cell Biology·Hai WuGerald R Crabtree

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Citations

Feb 1, 2012·Molecular Psychiatry·C L Raison, A H Miller
Mar 6, 2009·American Journal of Physiology. Cell Physiology·Ying ShaoMary C Farach-Carson
Jan 11, 2019·International Journal of Molecular Sciences·Darius Häusler, Martin S Weber

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