Monte Carlo modeling of a 6 and 18 MV Varian Clinac medical accelerator for in-field and out-of-field dose calculations: development and validation.

Physics in Medicine and Biology
Bryan Bednarz, X George Xu

Abstract

There is a serious and growing concern about the increased risk of radiation-induced second cancers and late tissue injuries associated with radiation treatment. To better understand and to more accurately quantify non-target organ doses due to scatter and leakage radiation from medical accelerators, a detailed Monte Carlo model of the medical linear accelerator is needed. This paper describes the development and validation of a detailed accelerator model of the Varian Clinac operating at 6 and 18 MV beam energies. Over 100 accelerator components have been defined and integrated using the Monte Carlo code MCNPX. A series of in-field and out-of-field dose validation studies were performed. In-field dose distributions calculated using the accelerator models were tuned to match measurement data that are considered the de facto 'gold standard' for the Varian Clinac accelerator provided by the manufacturer. Field sizes of 4 cm x 4 cm, 10 cm x 10 cm, 20 cm x 20 cm and 40 cm x 40 cm were considered. The local difference between calculated and measured dose on the percent depth dose curve was less than 2% for all locations. The local difference between calculated and measured dose on the dose profile curve was less than 2% in the plate...Continue Reading

References

Apr 1, 1996·Medical Physics·I KawrakowK Friedrich
Jun 1, 1997·International Journal of Radiation Oncology, Biology, Physics·D FollowillA Boyer
Apr 22, 1999·Physics in Medicine and Biology·R JerajP M Ostwald
Apr 5, 2002·Medical Physics·Daryoush Sheikh-Bagheri, D W O Rogers
Apr 16, 2003·International Journal of Radiation Oncology, Biology, Physics·Eric J Hall, Cheng-Shie Wuu
Dec 5, 2003·Physics in Medicine and Biology·Frank Verhaegen, Jan Seuntjens
Apr 21, 2005·Medical Physics·Rebecca M HowellGary D Fullerton
Jul 2, 2005·International Journal of Radiation Oncology, Biology, Physics·Stephen F KryIsaac I Rosen
Jul 2, 2005·International Journal of Radiation Oncology, Biology, Physics·Stephen F KryIsaac I Rosen
Dec 8, 2005·Physics in Medicine and Biology·J PenaM Pombar
Apr 29, 2006·Radiation Protection Dosimetry·H K KimJ K Lee
Jul 4, 2006·Radiation Protection Dosimetry·A FacureR C Falcão
Nov 28, 2006·International Journal of Radiation Oncology, Biology, Physics·Harald PaganettiThomas F Delaney
Dec 13, 2006·Medical Physics·Stephen F KryMohammad Salehpour
Oct 12, 2007·Medical Physics·Stephen F KryMohammad Salehpour
Jun 10, 2008·Physics in Medicine and Biology·X George XuHarald Paganetti

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Citations

Aug 16, 2011·Physics in Medicine and Biology·Henry WangLei Xing
Oct 8, 2011·Radiation Protection Dosimetry·John A Kalef-Ezra
Oct 1, 2009·Biomedical Imaging and Intervention Journal·S-T Chiu-Tsao, Mf Chan
May 6, 2011·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Janett LiebichUlla Ramm
Aug 13, 2015·Journal of Radiation Research·Isra Israngkul-Na-AyuthayaPhongpheath Pengvanich
Aug 28, 2015·Radiation Protection Dosimetry·Matthias Frankl, Rafael Macián-Juan
Oct 3, 2013·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Theocharis BerrisJohn Damilakis
Feb 6, 2015·Medical Physics·Adam J Uselmann, Bruce R Thomadsen
Dec 3, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Michael LishnerFrederic Amant
Jun 24, 2015·Journal of Applied Clinical Medical Physics·Strahinja StojadinovicTimothy D Solberg
Jan 16, 2013·Journal of Applied Clinical Medical Physics·Theocharis BerrisJohn Damilakis
Oct 9, 2013·Physics in Medicine and Biology·Phillip J TaddeiWayne D Newhauser
Feb 27, 2015·Physics in Medicine and Biology·Choonik LeeChoonsik Lee
Jul 22, 2011·Physics in Medicine and Biology·A JoostenR Moeckli
Feb 13, 2015·Physics in Medicine and Biology·Jérémi Vũ BezinIbrahima Diallo
Nov 4, 2017·Physics in Medicine and Biology·Kyle J GallagherPhillip J Taddei
Feb 14, 2017·Physics in Medicine and Biology·Nicolas ArborDaniel Husson
Jan 25, 2017·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Jérémi Vũ BezinIbrahima Diallo
Jan 15, 2021·Biomedical Physics & Engineering Express·William P DonahueJoyoni Dey
Apr 8, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Leonardo CatussoJoão V B Valença
Aug 23, 2021·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Hossein AslianFrancesco Longo
Aug 13, 2021·Physics in Medicine and Biology·Hyojun ParkChul Hee Min

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