PMID: 9651014Jul 3, 1998Paper

Monte Carlo simulation of source-excited in vivo x-ray fluorescence measurements of heavy metals

Physics in Medicine and Biology
J M O'MearaC E Svensson

Abstract

This paper reports on the Monte Carlo simulation of in vivo x-ray fluorescence (XRF) measurements. Our model is an improvement on previously reported simulations in that it relies on a theoretical basis for modelling Compton momentum broadening as well as detector efficiency. Furthermore, this model is an accurate simulation of experimentally detected spectra when comparisons are made in absolute counts; preceding models have generally only achieved agreement with spectra normalized to unit area. Our code is sufficiently flexible to be applied to the investigation of numerous source-excited in vivo XRF systems. Thus far the simulation has been applied to the modelling of two different systems. The first application was the investigation of various aspects of a new in vivo XRF system, the measurement of uranium in bone with 57Co in a backscatter (approximately 180 degrees) geometry. The Monte Carlo simulation was critical in assessing the potential of applying XRF to the measurement of uranium in bone. Currently the Monte Carlo code is being used to evaluate a potential means of simplifying an established in vivo XRF system, the measurement of lead in bone with 57Co in a 90 degrees geometry. The results from these simulations ma...Continue Reading

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Citations

Feb 13, 2001·Computers in Biology and Medicine·F H Al-GhorabieS H Al-Lyhiani
Jan 17, 2016·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·K Phanisree TimmarajuDavid R Chettle
Dec 5, 2008·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·R Taleei, M Shahriari
Jun 13, 2006·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Naseer AhmedJoanne M O'Meara
Sep 24, 2004·Physics in Medicine and Biology·S A Graham, J M O'Meara
Mar 22, 2007·Physics in Medicine and Biology·Marie Hansson, Mats Isaksson
Apr 2, 2009·Physics in Medicine and Biology·J M O'Meara, D E B Fleming
Mar 19, 2005·Physics in Medicine and Biology·Ryan C N StudinskiJoanne M O'Meara

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