PMID: 591941Dec 1, 1977

Mood change and magnesium. A possible interaction between magnesium and lithium?

The Journal of Nervous and Mental Disease
L Herzberg, B Herzeberg


Magnesium and lithium are chemically related. Magnesium is an essential ion in many enzyme systems and lithium is of value in the treatment of manic-depressive disease. A significant sex difference in mean plasma magnesium levels is reported in 44 depressed patients. It is suggested that further studies of magnesium metabolism are indicated and that they may provide a better understanding of manic-depressive disease and the mode of action of lithium.


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Jan 1, 1986·Journal of the American College of Nutrition·F W Lowenstein, M F Stanton
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Dec 1, 2009·Medical Hypotheses·George A Eby, Karen L Eby
Jun 14, 2018·BJPsych Open·Danny PhelanMarc Molendijk
Jan 1, 1986·Annals of the New York Academy of Sciences·C M BankiC D Kilts

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