Mood Differences Among Parkinson's Disease Patients With Mild Cognitive Impairment

The Journal of Neuropsychiatry and Clinical Neurosciences
Jacob D JonesDawn Bowers

Abstract

Studies with healthy elderly adults suggest that apathy, depression, and anxiety are more common among individuals with mild cognitive impairment (MCI). This study examined differences in mood/amotivational symptoms among patients with Parkinson's disease (PD) with and without MCI. Patients with PD (N=214) underwent neurocognitive evaluations including assessment of apathy (Apathy Scale), depression (Beck Depression Inventory-II), and trait anxiety (State-Trait Anxiety Inventory trait scale). Trait anxiety and depression were more severe in patients with PD with MCI. Delineation of MCI into amnestic and nonamnestic subtypes revealed greater depression, apathy, and anxiety among patients with PD with amnestic MCI relative to cognitively intact patients with PD. Patients with PD and MCI report greater mood symptoms compared to patients with PD who are cognitively intact.

Citations

Apr 19, 2017·International Psychogeriatrics·Chelsea ShermanKrista L Lanctôt
Oct 17, 2017·Journal of the International Neuropsychological Society : JINS·Sarah M SzymkowiczDawn Bowers
Nov 20, 2019·Movement Disorders : Official Journal of the Movement Disorder Society·Chiara BaianoGabriella Santangelo
Sep 2, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Jéssica Soares FelicianoJanaine Cunha Polese
Feb 7, 2017·Journal of the International Neuropsychological Society : JINS·Jacob D JonesDawn Bowers
Feb 12, 2021·The Clinical Neuropsychologist·Adrianna M RatajskaDawn Bowers
Mar 5, 2021·Current Psychiatry Reports·Sandra Abou KassmAntoine Pelissolo
Apr 17, 2021·Neuropsychology Review·Elizabeth R WallaceLisa M Koehl
Feb 10, 2021·Harvard Review of Psychiatry·Alan A Baumeister

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