MOPED enables discoveries through consistently processed proteomics data

Journal of Proteome Research
Roger HigdonEugene Kolker

Abstract

The Model Organism Protein Expression Database (MOPED, http://moped.proteinspire.org) is an expanding proteomics resource to enable biological and biomedical discoveries. MOPED aggregates simple, standardized and consistently processed summaries of protein expression and metadata from proteomics (mass spectrometry) experiments from human and model organisms (mouse, worm, and yeast). The latest version of MOPED adds new estimates of protein abundance and concentration as well as relative (differential) expression data. MOPED provides a new updated query interface that allows users to explore information by organism, tissue, localization, condition, experiment, or keyword. MOPED supports the Human Proteome Project's efforts to generate chromosome- and diseases-specific proteomes by providing links from proteins to chromosome and disease information as well as many complementary resources. MOPED supports a new omics metadata checklist to harmonize data integration, analysis, and use. MOPED's development is driven by the user community, which spans 90 countries and guides future development that will transform MOPED into a multiomics resource. MOPED encourages users to submit data in a simple format. They can use the metadata check...Continue Reading

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Citations

Jan 25, 2014·Omics : a Journal of Integrative Biology·Eugene KolkerGregory Yandl
Jun 10, 2014·Omics : a Journal of Integrative Biology·Elizabeth MontagueEugene Kolker
Nov 19, 2014·Journal of Chemical Information and Modeling·Cerys WilloughbyJeremy G Frey
Nov 18, 2015·Omics : a Journal of Integrative Biology·Eugene KolkerNatali Kolker
Apr 17, 2015·Journal of Proteome Research·Roger Higdon, Eugene Kolker
Nov 8, 2014·Computational and Structural Biotechnology Journal·Bjoern TitzManuel C Peitsch
Nov 19, 2014·Nucleic Acids Research·Elizabeth MontagueEugene Kolker
Feb 6, 2014·Journal of Proteome Research·Eugene Kolker, Elizabeth Stewart
Aug 23, 2020·International Journal of Molecular Sciences·Marco PelinAurelia Tubaro

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