Morbidity and mortality after D2 gastrectomy for gastric cancer: results of the Italian Gastric Cancer Study Group prospective multicenter surgical study

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
M DegiuliF Calvo

Abstract

To investigate whether pancreas preservation together with a strict quality-control system could ameliorate the outcome of D2 resections for gastric cancer in Western patients. Italian patients with potentially curable proven adenocarcinoma of the stomach were registered from nine general and/or university hospitals in the area of Turin, Northern Italy. The study was performed according to the guidelines of the Japanese Research Society for Gastric Cancer (JRSGC). A strict quality-control system was guaranteed by a supervising surgeon of the reference center, who had stayed at the National Cancer Center Hospital, Tokyo, to learn the standard D2 gastrectomy. The standard procedure entailed removal of the level 1 and 2 lymph nodes. During total gastrectomy, the pancreas was preserved according to the Maruyama technique. Between May 1994 and December 1996, 191 eligible patients were entered onto the study. The mean number of lymph nodes removed was 39. The overall morbidity rate was 20.9%. Surgical complications were observed in 16.7% of patients. Reoperation was necessary in six patients and was always successful. The overall hospital mortality rate was 3.1%; it was higher after total gastrectomy (7.46%) than after distal gastrec...Continue Reading

Citations

Jan 26, 2007·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·S A Hundahl
Apr 22, 2008·Arquivos De Gastroenterologia·Fernando O SouzaJuarez Chiesa
Nov 26, 2008·World Journal of Gastroenterology : WJG·Dao-Jun GongLi Chen
Sep 10, 2009·The Oncologist·Sam S Yoon, Han-Kwang Yang
Mar 18, 2011·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Alberto PatritiLuciano Casciola
Mar 15, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Ugwuji N Maduekwe, Sam S Yoon
Apr 20, 2012·Journal of Surgical Oncology·Benjamin Schmidt, Sam S Yoon
Feb 9, 2012·International Journal of Surgical Oncology·Shigeyuki TamuraHirofumi Miki
Apr 30, 2013·World Journal of Surgery·Lorenzo Ferri
May 14, 2014·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Kyung-Goo LeeHan-Kwang Yang
Apr 25, 2014·Gastroenterology Report·Marissa MontgomerySteven Brower
Jul 19, 2017·World Journal of Surgical Oncology·Tianxiang ChenXiang Da Eric Dong
Jan 30, 2018·World Journal of Gastroenterology : WJG·Rossella ReddavidMaurizio Degiuli
Nov 5, 2003·Journal of Surgical Oncology·Koen C M J Peeters, Cornelis J H van de Velde
Jun 17, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Takeshi SanoKunio Okajima
Aug 11, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Roderich E Schwarz, David D Smith
Jan 26, 2007·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·M SasakoT Sano
Jun 3, 2005·The British Journal of Surgery·D J ParkK J Choe
Jul 2, 2005·International Journal of Clinical Oncology·Mitsuru Sasako
Mar 13, 2008·Journal of the National Cancer Institute·Francesco Di CostanzoRoberta Camisa
Feb 27, 2010·The British Journal of Surgery·M DegiuliUNKNOWN Italian Gastric Cancer Study Group
Sep 8, 2010·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Yutaka Tanizawa, Masanori Terashima
Nov 26, 2009·The Journal of International Medical Research·R B He, Jun-qiang Chen
Apr 21, 2007·Digestive Surgery·M SasakoT Sano
Oct 23, 2015·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Daniel P NussbaumAlexander Perez
Mar 22, 2016·Journal of Surgical Oncology·Reese W RandleKonstantinos I Votanopoulos
Sep 24, 2016·Annals of the Royal College of Surgeons of England·T TakiK Yanaga
May 8, 2019·Acta chirurgica Belgica·Piotr KuligPiotr Richter
Jan 1, 2004·Irish Journal of Medical Science·J A McCulloughJ V Reynolds
Aug 18, 2005·The British Journal of Surgery·Y KoderaUNKNOWN Gastric Cancer Surgery Study Group of Japan Clinical Oncology Group
Jan 7, 2005·The British Journal of Surgery·P McCullochJ J Gama-Rodrigues
Apr 13, 2006·World Journal of Gastroenterology : WJG·Yasuhiro KoderaAkimasa Nakao
May 11, 2004·Langenbeck's Archives of Surgery·Norihiro Yuasa, Yuji Nimura
Oct 9, 2012·Upsala Journal of Medical Sciences·Ji-Feng FengXing-Ming Zhou
Jun 20, 2007·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Michel PortanovaJorge Orrego

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