Morbidity in schistosomiasis: an update

Current Opinion in Infectious Diseases
B J Vennervald, D W Dunne

Abstract

Schistosomiasis is an important poverty-related health problem and more than 200 million people are infected. This review summarizes papers from April 2003 to June 2004 with a focus on schistosomiasis morbidity and the various factors that affect the level of morbidity in endemic populations. The aim is to provide an update on the current state of knowledge and, hopefully, thereby stimulate continued research interest in this important area. Research into the immune responses associated with severe morbidity has provided new insights into the mechanisms of immune regulation as well as the role of genetic predisposition to periportal fibrosis. Malaria and schistosomiasis are co-endemic and co-infection with malaria may increase the level of morbidity in hepatosplenic schistosomiasis, and alter the host immune response towards schistosome antigens. Schistosome infections may render the host more susceptible to human immunodeficiency virus infection by either interfering with immune responses or increasing the risk of transmission due to genital lesions. An important advance in schistosomiasis research, and parasite genomics, is the recent availability of two major Schistosoma mansoni and Schistosoma japonicum DNA bioinformatic re...Continue Reading

References

Apr 1, 1990·Gut·A R MohamedM I Yasawy
Apr 13, 2000·The American Journal of Tropical Medicine and Hygiene·C M ReimertB J Vennervald
Sep 21, 2000·Acta Tropica·L ChitsuloL Savioli
Oct 3, 2000·Advances in Parasitology·C F Hatz
May 30, 2002·Genome Génome / Conseil National De Recherches Canada·Chikako ShindoKazuhiko Noda
Jul 5, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Sandrine HenriAlain J Dessein
May 15, 2003·Acta Tropica·Joachim Richter
May 15, 2003·Acta Tropica·G Richard Olds
Jul 31, 2003·Transactions of the Royal Society of Tropical Medicine and Hygiene·Alison M ElliottJames A Whitworth
Sep 16, 2003·Nature Genetics·Sergio Verjovski-AlmeidaEmmanuel Dias-Neto
Sep 19, 2003·International Journal for Parasitology·Rupert J Quinnell
Sep 19, 2003·Lancet·Joachim RichterDieter Häussinger
Oct 29, 2003·Trends in Parasitology·Alan FenwickMatthew H Todd
Nov 11, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Christophe ChevillardAlain J Dessein
Nov 14, 2003·Annals of Tropical Medicine and Parasitology·C W A NausL van Lieshout
Dec 6, 2003·BMJ : British Medical Journal·Stephen Pincock
Dec 10, 2003·Genome Génome / Conseil National De Recherches Canada·G Brian Golding
Dec 31, 2003·Proceedings of the National Academy of Sciences of the United States of America·Margaret M Mentink-KaneThomas A Wynn
Jan 7, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Mark BoothDavid W Dunne
Jan 20, 2004·Tropical Medicine & International Health : TM & IH·Marieke J van der WerfJ D F Habbema
Jan 24, 2004·Lancet·Donato Cioli, Piero Liberti
Feb 24, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Matthias HesseThomas A Wynn
Mar 5, 2004·Tropical Medicine & International Health : TM & IH·Narcis B KabatereineAmbrose W Onapa
Mar 5, 2004·Expert Opinion on Pharmacotherapy·Jürg Utzinger, Jennifer Keiser

❮ Previous
Next ❯

Citations

Jan 27, 2012·Inflammopharmacology·Eman SaidElsayed M Ammar
Jul 2, 2004·Transactions of the Royal Society of Tropical Medicine and Hygiene·F RemoueG Riveau
Dec 13, 2006·Immunology and Cell Biology·Mark S WilsonThomas A Wynn
Nov 7, 2009·Journal of Tropical Pediatrics·Jessica Agnew-BlaisMary Ngoma
Aug 18, 2010·International Journal of Clinical Practice. Supplement·A HovnanianR Souza
Aug 10, 2011·Infection and Immunity·Rita BhardwajPatrick J Skelly
Mar 3, 2007·The Journal of Clinical Investigation·Thomas A Wynn
Nov 30, 2012·Parasites & Vectors·Humphrey D MazigoDavid W Dunne
Oct 25, 2012·PLoS Neglected Tropical Diseases·José C Sousa-FigueiredoJ Russell Stothard
Nov 3, 2010·The American Journal of Tropical Medicine and Hygiene·Martha BetsonJ Russell Stothard
Apr 6, 2013·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Oyetunde T Salawu, Alexander B Odaibo
Oct 9, 2014·Thrombosis Research·Akram A Da'dara, Patrick J Skelly
Jun 15, 2007·Molecular and Biochemical Parasitology·Mariana SimõesGuilherme Oliveira
Aug 25, 2015·International Journal of Public Health·Chalotte Willemann StecherEskild Petersen
Sep 6, 2005·Parasite Immunology·W E Secor
Sep 6, 2005·Parasite Immunology·A P Mountford
Oct 15, 2009·Parasite Immunology·Z A Andrade
Apr 14, 2007·Parasite Immunology·C B Cêtre-SossahW E Secor
Dec 29, 2007·The Journal of Pathology·T A Wynn
Mar 19, 2009·Parasite Immunology·M L BurkeD P McManus
Apr 7, 2011·American Journal of Physical Anthropology·Amber Campbell HibbsGeorge Armelagos
May 23, 2006·Trends in Parasitology·Narcis B KabatereineLynsey Blair
Dec 29, 2005·Trends in Parasitology·Frederico G C AbathSilvia M L Montenegro
Aug 4, 2005·Molecular and Biochemical Parasitology·Jason M CorrentiEdward J Pearce
Apr 26, 2015·Acta Tropica·Tina Tu-Wen ChenShih-Yi Peng
Jan 28, 2015·Acta Tropica·Anna Overgaard KildemoesBirgitte Jyding Vennervald
Feb 26, 2014·International Journal of Surgery Case Reports·Raymond Ladu
May 8, 2007·International Journal for Parasitology·Jason M CorrentiEdward J Pearce
Jan 23, 2015·Veterinary Research Communications·G B AndradeH L Lenzi
Jun 5, 2014·Purinergic Signalling·Akram A Da'daraPatrick J Skelly
Jul 30, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas CrellenJoanne P Webster

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.