More similar than you think: Frog metamorphosis as a model of human perinatal endocrinology

Developmental Biology
Daniel R Buchholz

Abstract

Hormonal control of development during the human perinatal period is critically important and complex with multiple hormones regulating fetal growth, brain development, and organ maturation in preparation for birth. Genetic and environmental perturbations of such hormonal control may cause irreversible morphological and physiological impairments and may also predispose individuals to diseases of adulthood, including diabetes and cardiovascular disease. Endocrine and molecular mechanisms that regulate perinatal development and that underlie the connections between early life events and adult diseases are not well elucidated. Such mechanisms are difficult to study in uterus-enclosed mammalian embryos because of confounding maternal effects. To elucidate mechanisms of developmental endocrinology in the perinatal period, Xenopus laevis the African clawed frog is a valuable vertebrate model. Frogs and humans have identical hormones which peak at birth and metamorphosis, have conserved hormone receptors and mechanisms of gene regulation, and have comparable roles for hormones in many target organs. Study of molecular and endocrine mechanisms of hormone-dependent development in frogs is advantageous because an extended free-living lar...Continue Reading

References

Nov 1, 1991·In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association·A Ishizuya-Oka, A Shimozawa
Jan 1, 1991·Annual Review of Physiology·C R Mendelson, V Boggaram
Sep 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·Y YaoitaD D Brown
Feb 15, 1981·American Journal of Obstetrics and Gynecology·B R CarrJ C Porter
Oct 1, 1984·General and Comparative Endocrinology·G Jolivet Jaudet, J Leloup Hatey
Jan 1, 1994·Reproduction, Fertility, and Development·G C Liggins
Oct 1, 1993·Environmental Health Perspectives·T ColbornA M Soto
Apr 1, 1993·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·J R Tata
Jan 1, 1995·Reproduction, Fertility, and Development·A L Fowden
Jun 15, 1996·Microscopy Research and Technique·A Ishizuya-Oka
Feb 25, 1999·Gastroenterology·R K MontgomeryR J Grand
Feb 25, 2000·Neuroscience Letters·N Hadj-SahraouiB Demeneix
Jun 30, 2000·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·L M SachsA Ishizuya-Oka
Nov 15, 2000·Proceedings of the National Academy of Sciences of the United States of America·L M Sachs, Y B Shi
Aug 2, 2001·The Journal of Endocrinology·A L FowdenA J Forhead
Mar 14, 2002·Proceedings of the National Academy of Sciences of the United States of America·Beatriz MorteJuan Bernal
Jul 4, 2002·The Journal of Biological Chemistry·Wayland LimJ David Furlow
Feb 20, 2003·Trends in Endocrinology and Metabolism : TEM·Frédéric Flamant, Jacques Samarut
Aug 21, 2003·General and Comparative Endocrinology·Shawichi IwamuroSakae Kikuyama
Apr 2, 2004·The Journal of Biological Chemistry·J David FurlowThomas S Scanlan
Jul 9, 2004·Proceedings of the National Academy of Sciences of the United States of America·Wilfried MaiJacques Samarut
Aug 5, 2004·The Journal of Clinical Endocrinology and Metabolism·Robert HumeUNKNOWN Scottish Preterm Thyroid Group
Dec 21, 2004·Treatments in Respiratory Medicine·David G Grier, Henry L Halliday
Feb 4, 2005·The New England Journal of Medicine·Shuji FukataMasahiro Sugawara
Apr 19, 2005·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Atsuko Ishizuya-Oka
Nov 4, 2005·General and Comparative Endocrinology·Daniel R BuchholzYun-Bo Shi
Jul 5, 2006·Environmental Health Perspectives·Tyrone B HayesMable Tsui
Jan 16, 2007·The Journal of Biological Chemistry·Bindu D PaulYun-Bo Shi
Apr 24, 2007·Developmental Biology·Donald D Brown, Liquan Cai
May 8, 2007·Mechanisms of Development·Yukiyasu SatoYun-Bo Shi

❮ Previous
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Citations

Jan 29, 2016·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Mijal J DistlerAndrea G Pozzi
May 29, 2016·BMC Genomics·Ricardo N AlvesDeborah M Power
Jun 15, 2016·Developmental Biology·Fernando Faunes, Juan Larraín
Jan 22, 2017·Genesis : the Journal of Genetics and Development·Laurent M Sachs, Daniel R Buchholz
Jan 20, 2017·Nature Protocols·Gabriela Edwards-FaretJuan Larraín
Apr 1, 2018·The Journal of Comparative Neurology·Gabriela Edwards-FaretJuan Larraín
May 18, 2018·Cold Spring Harbor Protocols·Daniel R Buchholz, Yun-Bo Shi
Jun 23, 2019·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Yinan HuSarah McMenamin
Jun 8, 2017·Endocrinology·Bilal B MughalBarbara A Demeneix
Jun 4, 2019·Frontiers in Endocrinology·Anita A ThambirajahCaren C Helbing
Nov 8, 2018·Perspectives on Behavior Science·Peter PohlJennifer Lee Moschella
Jan 3, 2018·Toxicological Sciences : an Official Journal of the Society of Toxicology·Justin D TaftWade H Powell
Sep 22, 2017·Zebrafish·Sarah McMenaminWiliam James Cooper
Nov 3, 2017·Cold Spring Harbor Protocols·Matthew D PatmannDaniel R Buchholz
Jan 29, 2020·Proceedings of the National Academy of Sciences of the United States of America·Gayani SenevirathneNeil H Shubin
Nov 1, 2020·Journal of Medical Ethics·Daniel RodgerBruce Philip Blackshaw
Oct 26, 2020·Endocrinology·Leena H ShewadeDaniel R Buchholz
Feb 3, 2021·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Alicia TribondeauNicolas Buisine
Dec 29, 2020·Genesis : the Journal of Genetics and Development·Cameron R T Exner, Helen Rankin Willsey
Feb 10, 2021·Endocrinology·Yun-Bo Shi
Mar 17, 2021·The Journal of Steroid Biochemistry and Molecular Biology·Janina TokarzJerzy Adamski
Dec 11, 2017·Best Practice & Research. Clinical Endocrinology & Metabolism·Keisuke Ikegami, Takashi Yoshimura
Aug 30, 2018·Hormone Research in Pædiatrics·Giovanni PreziosoFrancesco Chiarelli

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