More than Just Minutes of Stiffness in the Morning: Report from the OMERACT Rheumatoid Arthritis Flare Group Stiffness Breakout Sessions

The Journal of Rheumatology
Ana-Maria OrbaiRA Flare Group Steering Committee

Abstract

Stiffness was endorsed within the rheumatoid arthritis (RA) flare core domain set at the previous Outcome Measures in Rheumatology meeting (OMERACT 11). Two stiffness breakout groups at the present OMERACT 12 RA flare workshop discussed results of new qualitative studies in RA stiffness. Results from 2 independent studies of RA stiffness were presented to breakout group participants, followed by group discussions about stiffness measurement. Both studies identified stiffness as complex, variable with the level of disease activity, and as encompassing concepts of impact, intensity, timing, location, and duration. That stiffness has an effect on multiple dimensions of health was a common finding. Participants agreed that stiffness is an important aspect of RA flare. Whether measuring only morning stiffness duration, the traditional approach in RA, was sufficient in coverage of the concept was unclear. Groups agreed that more research on stiffness measurement is needed considering the importance patients place on the effect of stiffness. Results from independent studies highlight stiffness effect as an important feature of RA, in addition to intensity, timing, location, and duration. Additional work is needed to identify optimal w...Continue Reading

References

Aug 3, 2011·The Journal of Rheumatology·Rieke AltenUNKNOWN OMERACT RA Flare Definition Working Group
Aug 3, 2011·The Journal of Rheumatology·Clifton O BinghamUNKNOWN OMERACT RA Flare Definition Working Group
May 9, 2012·Annals of the Rheumatic Diseases·Frank ButtgereitKenneth G Saag
Jul 10, 2012·Annals of the Rheumatic Diseases·Susan J BartlettUNKNOWN OMERACT RA Flare Working Group
Mar 4, 2014·Journal of Clinical Epidemiology·Maarten BoersPeter Tugwell
Mar 4, 2014·The Journal of Rheumatology·Maarten BoersPeter Tugwell

❮ Previous
Next ❯

Citations

Jan 11, 2017·Current Opinion in Rheumatology·Betty Hsiao, Liana Fraenkel
Feb 15, 2019·Arthritis Care & Research·Mia GlerupUNKNOWN Nordic Study Group of Pediatric Rheumatology
Aug 20, 2020·Musculoskeletal Care·Hugh WatsonLars Erik Bartels
Aug 16, 2021·Journal of Bodywork and Movement Therapies·Guillaume LeonardLucie Brosseau

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.