More than valve repair: Effect of cone reconstruction on right ventricular geometry and function in patients with Ebstein anomaly

International Journal of Cardiology
Xiao LiYu-Cheng Chen

Abstract

Cone reconstruction is a novel surgical procedure for tricuspid valve repair in Ebstein anomaly. This study examined the effect of cone reconstruction on right ventricle (RV) geometry, function, and synchronization. Twenty-one patients (4-49 year-old) underwent cone reconstruction were enrolled, and matched with healthy individuals. Pre-operative and follow-up echocardiography was performed along with cardiac magnetic resonance (CMR) imaging in 18 patients. A new parameter, tricuspid annular movement synchronicity index (TAMSI), was used to describe global synchronization of RV in the annular plane. TAMSI was defined as standard deviation of the systolic excursion of the hinge points of the three leaflets divided by their average value. After 9.1 (range 1-12) months follow-up, there were no deaths; tricuspid regurgitation was reduced from moderate/severe to mild or less in 95.2% of patients. In 18 patients with both pre and post CMR data, functional RV volume decreased after repair (134.3 ± 58.3 ml/m(2) to 96.6 ± 29.6 ml/m(2); P=0.001), while ejection fraction was not significantly altered (38.2 ± 9.2% to 36.5 ± 8.5%; P=0.357). TAMSI was significantly reduced after surgery, from 0.613 ± 0.220 to 0.169 ± 0.088 (P<0.001). A value...Continue Reading

References

Mar 1, 1953·Circulation Research·R F RUSHMERC WAGNER
Feb 16, 2011·The Journal of Thoracic and Cardiovascular Surgery·Jinfen LiuHaifa Hong
Mar 20, 2012·American Heart Journal·Alaina K KippsJonathan Rhodes
Jan 1, 2014·Congenital Heart Disease·Heather N AndersonFrank Cetta
Feb 24, 2015·The Journal of Thoracic and Cardiovascular Surgery·Joseph A Dearani
May 9, 2015·Canadian Journal of Public Health = Revue Canadienne De Santé Publique·Khadija Ibrahim

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Citations

Oct 20, 2017·Interactive Cardiovascular and Thoracic Surgery·Dongxu LiQi An
Sep 29, 2017·Cardiovascular Research·Odilia I WoudstraVincent M Christoffels
Sep 28, 2018·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Dan YangYu-Cheng Chen
May 23, 2018·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Rebecca S BeroukhimAndrew J Powell
Nov 10, 2020·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Tim LeinerDudley J Pennell
Jan 28, 2021·Journal of Cardiac Surgery·Evan P Rotar, Irving L Kron
Jun 15, 2019·Cardiology in the Young·Kristen L SessionsJonathan N Johnson
May 10, 2021·Seminars in Thoracic and Cardiovascular Surgery·Antonia SchulzChristopher W Baird

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