Morphea - selected local treatment methods and their effectiveness

Reumatologia
Joanna NarbuttAleksandra Lesiak

Abstract

Localised scleroderma is an uncommon connective tissue disease of multifactorial aetiology occurring in the paediatric and adult population. It is relatively difficult to conduct any research on the subject of this disease entity treatment due to the low number of patients suffering from morphea, a tendency of the disease to remit spontaneously, and not yet well recognised aetiology. Hence, there has been developed no causal treatment of well-proven effectiveness, and schedules of symptomatic therapy are not yet clearly determined. The paper depicts most widely used topical treatment methods in morphea therapy, which due to minor risk of systemic adverse effects seem to be a beneficial therapeutic alternative. The main aim of this article was to analyse different topical treatment options used in localised scleroderma therapy and to indicate the most appropriate, safe, and effective one.

Citations

Aug 20, 2019·BMJ Case Reports·Claire SethuDiana Slade-Sharman
Jun 14, 2020·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·Hannah StrohFerdinand Toberer
Jun 2, 2020·Indian Dermatology Online Journal·Renu GeorgeT Sathish Kumar

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