Morphine administration in horses anaesthetized for upper respiratory tract surgery

Veterinary Anaesthesia and Analgesia
Emma J LovePamela J Murison

Abstract

To determine the effect of morphine administration on commonly monitored cardio-respiratory variables and recovery quality in horses undergoing anaesthesia and surgery. Prospective, randomized clinical study. Thirty-eight thoroughbred horses, 32 geldings and six mares, 3-13 years old, weighing 411-600 kg. A standard anaesthetic technique was used. Twenty minutes after induction of anaesthesia horses received 0.1 mg kg(-1) (0.1 m) or 0.2 mg kg(-1) (0.2 m) morphine by intravenous injection. A control group did not receive morphine. Heart rate, respiratory rate (fr), mean arterial pressure (MAP) and blood gases were measured before morphine administration and every 10 minutes thereafter. Horses were positioned for 35 minutes in right lateral recumbency for tension palatoplasty by cautery and were then moved into dorsal recumbency for additional intraluminal surgery comprising one or more of aryepiglottic fold resection, sub-epiglottal mucosal resection, ventriculectomy and cordectomy. A subjective recovery score from 0 (worst) to 5 (best) was assigned by a single observer who was unaware of treatment group. Two-way repeated measures anova, one-way anova, Kruskal-Wallis test, Mann-Whitney test, Pearson and Spearman correlation coef...Continue Reading

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Citations

May 25, 2012·American Journal of Veterinary Research·Juliana P FigueiredoRichard Sams
Jun 6, 2013·The Veterinary Record·E J LoveJ Murrell
Aug 14, 2013·Research in Veterinary Science·M A Chesnel, R E Clutton
Apr 1, 2014·The Veterinary Clinics of North America. Equine Practice·Alessio Vigani, Fernando L Garcia-Pereira
Nov 9, 2010·The Veterinary Clinics of North America. Equine Practice·R Eddie Clutton
Nov 9, 2010·The Veterinary Clinics of North America. Equine Practice·Sheilah A Robertson, L Chris Sanchez
Oct 24, 2007·Peptides·Richard J Bodnar
Mar 7, 2013·Veterinary Anaesthesia and Analgesia·Sílvia E R S LorenaJosé E Corrente
Mar 22, 2014·Equine Veterinary Journal·L C Sanchez, S A Robertson
Sep 23, 2018·Journal of Veterinary Pharmacology and Therapeutics·Tamara L GrubbJennifer L Davis
Mar 7, 2014·Equine Veterinary Journal·F D WohlfenderR Bettschart-Wolfensberger
Feb 5, 2021·Veterinary Anaesthesia and Analgesia·Cristina de Miguel GarciaRobin D Gleed
Jul 3, 2021·Animals : an Open Access Journal From MDPI·Miguel Gozalo-Marcilla, Simone Katja Ringer
Aug 22, 2021·Journal of Equine Veterinary Science·F Javier López-SanrománG Manso-Díaz

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