Morphofunctional organization in three patients with unilateral polymicrogyria: combined use of diffusion tensor imaging and functional magnetic resonance imaging

Brain & Development
Mitsutoshi MunakataKazuie Iinuma

Abstract

We examined the fiber organization of the brain in three patients with unilateral polymicrogyria (PMG) using diffusion tensor imaging (DTI) in combination with functional magnetic resonance imaging (fMRI). DTI revealed altered fiber tract architecture in patients with PMG. Long projection fibers, such as the corticospinal tract, were reduced the most, whereas long association fibers were less affected. The diminution of the fiber tracts was relevant to the loss of functionality of the PMG-affected cortex. Our preliminary study suggests that the combination of DTI and fMRI reinforces the clinical assessment of functionality in PMG.

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Citations

Sep 18, 2007·Epilepsia·Francine ChassouxBertrand Devaux
Nov 13, 2007·Psychophysiology·Elena RykhlevskaiaMonica Fabiani
Nov 14, 2006·Seizure : the Journal of the British Epilepsy Association·Leonardo BonilhaPaul Morgan
Sep 15, 2016·Journal of Child Neurology·Sureyya Burcu GörkemAbdulhakim Coskun
May 4, 2007·Journal of Neurophysiology·A Zsombok, K M Jacobs

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