Morphogenetic origin of natural variation

Bio Systems
V G Cherdantsev, V A Scobeyeva

Abstract

We studied individual pathways of gastrulation in two related amphibian species making an emphasis on the developmental dynamics of normal variation in the geometry of gastrulation movements. Analyzing the variation dynamics, we show that the linear succession of developmental stages is a secondary phenomenon disguising self-oscillations that lie at the heart of the dorsal blastopore lip morphogenesis. Characteristic features of the equations derived to describe the oscillations are, first, their dependence only on the movement geometry and, second, including of the dynamics of spatial variance directly into the movement equations, making it clear that the reasons for variability of morphogenesis are the same that for morphogenesis itself. The equations describing morphogenetic oscillations are mathematically similar to those describing natural selection in that the system tends to minimize its variance, individual or within-individual one, but the spatially uniform state turns to be unstable. Comparing of the dynamics of natural developmental variation in gastrulation in two frog species shows that, depending on the mechanics and geometry mass cell movements, different types of gastrulation movements have different proportions...Continue Reading

References

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May 23, 2012·Bio Systems·Valeria V IsaevaEugene V Presnov
May 23, 2012·Bio Systems·Vladimir G Cherdantsev, Olga V Grigorieva

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Citations

May 23, 2012·Bio Systems·Vladimir G Cherdantsev, Olga V Grigorieva
Apr 3, 2014·Bio Systems·Abir U Igamberdiev
Jun 25, 2014·Bio Systems·Olga V Grigorieva, Vladimir G Cherdantsev

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