PMID: 590573Nov 1, 1977

Morphologic basis for the common action of the nervous and hormonal control of gastric activity

Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova
I A Solov'eva, P K Klimov


In adult dogs and white Wistar rats, relationships between the automonic nerve endings, mucosal endocrine cells, mast cells, and blood capillaries in the gastric wall were studied with the aid of electron microscopy. A close association of 3 components of the regulatory mechanisms: neural, hormonal, and humoral, in the form of the triad comprising endocrine cells, autonomic nerve endings, and blood capillaries, was revealed, with no true synapses between them. Accumulations of the granules of the endocrine cells, synaptic vesicles of the autonomic nerves, and the pinocytose vesicles of the capillary endothelium were seen at inner surface of the cells' membranes which is the morphological indication of the physiological function. The data obtained suggest that the interaction between the 3 above components is realised through the diffuse synapses, and indicate that the interstitium of the digestive tract wall is the area of integration of the neural and the hormonal links of neuro-homoral visceral reflexes.

Related Concepts

Blood Capillaries
Cytoplasmic Granules
Canis familiaris
Structure of Pyloric Gland
Mast Cell
Electron Microscopy
Pyloric Antrum

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.