Morphologic criteria for the preliminary identification of Fusarium, Paecilomyces, and Acremonium species by histopathology

American Journal of Clinical Pathology
K LiuW A Schell

Abstract

Nontraditional human pathogenic fungi, including Fusarium, Paecilomyces, and Acremonium species, have been increasingly documented as agents of infection in immunocompromised patients and, occasionally, in normal hosts. Although definitive identification of these fungi requires culture, they often can be identified provisionally in tissue sections by a combination of histologic features, including hyaline septate hyphae and characteristic reproductive structures known as phialides and phialoconidia. These morphologic characteristics, although familiar to mycologists, are easily overlooked by histopathologists; as a result, Fusarium species and Paecilomyces lilacinus are frequently misidentified in tissue sections as Aspergillus or Candida species. We identified 19 culture-proved cases of infection with species of Fusarium, Paecilomyces, or Acremonium; retrospectively reviewed histologic specimens stained by routine hematoxylin and eosin, Gomori methenamine silver, and/or periodic acid-Schiff stains; and delineated morphologic criteria that will help pathologists make a preliminary identification of these fungi by histopathology. Adventitious sporulation was found in 9 of 9 infections caused by Paecilomyces species, 7 of 10 infe...Continue Reading

Citations

Jun 29, 2001·Transplant Infectious Disease : an Official Journal of the Transplantation Society·T J Walsh, A H Groll
Oct 15, 2003·Clinical Microbiology Reviews·Philip A Thomas
Feb 18, 2011·Transplant Infectious Disease : an Official Journal of the Transplantation Society·M KappG Stuhler
May 3, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Philip A ThomasJ Kaliamurthy
Sep 28, 2012·Journal of Clinical Microbiology·Carolyn O S NealS Arunmozhi Balajee
Dec 23, 2017·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Jean MeyerJoachim Spergser
Aug 26, 2004·Antimicrobial Agents and Chemotherapy·William J SteinbachDaniel K Benjamin
Jan 8, 2004·Journal of Chemotherapy·W J Steinbach, J R Perfect
Apr 6, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·John R Perfect
Jun 15, 2006·Medical Mycology·Josep GuarroG Sybren de Hoog
Apr 12, 2005·Transplant International : Official Journal of the European Society for Organ Transplantation·Jorge GarbinoChristian Van Delden
May 5, 2010·Journal of the American Animal Hospital Association·Danielle R PawloskiDeanna A Sutton
Jan 22, 2010·Critical Reviews in Microbiology·Michael A Pfaller, Daniel J Diekema
Oct 16, 2007·Clinical Microbiology Reviews·Marcio Nucci, Elias Anaissie
May 31, 2015·Mycopathologia·Seyed Jamal HashemiMehdi Nazeri
Sep 8, 2017·Frontiers in Microbiology·Danielly C M de SequeiraCintia de Moraes Borba
Apr 20, 2002·Current Opinion in Infectious Diseases·Aditya K. GuptaRichard C. Summerbell
Nov 20, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·T ChouakiC Hennequin
Feb 24, 2004·Infection and Immunity·Montserrat OrtonedaAntonio Di Pietro
Apr 22, 2005·Dermatologic Therapy·Priya VenkatesanSarah A Myers
Jun 4, 2005·The Laryngoscope·Christopher Y ChangGregory F Hulka
Sep 11, 2004·International Journal of Dermatology·Virginia C HallJohn S Walsh
Apr 22, 2004·The British Journal of Dermatology·S-F KanW-R Lee
Dec 14, 2004·Pediatric Blood & Cancer·Yu-Hsiang ChangKai-Hsin Lin
Nov 27, 2010·Medical Mycology·Shiva BalasinghamDeanna A Sutton
May 3, 2013·Current Medical Research and Opinion·John R Perfect
Mar 18, 2009·Medical Mycology·S Arunmozhi Balajee
Nov 2, 2019·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Victor G Prieto
Aug 26, 2000·Scandinavian Journal of Infectious Diseases·A WarrisT G Abrahamsen
Jul 3, 2013·Case Reports in Infectious Diseases·Bruna SteinerLuciano Z Goldani
Nov 6, 2009·Medical Mycology·María RiveroJuan Luis Rodríguez-Tudela
Apr 24, 2010·Transplant Infectious Disease : an Official Journal of the Transplantation Society·J-E KimK-C Moon

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