PMID: 9182315Mar 1, 1997Paper

Morphologic MR imaging with T1-weighted sequences for radiotherapy goal volume definition of intracranial tumors. Comparison with FLASH-Turbo-FLASH and SE sequences

Der Radiologe
H HawighorstG van Kaick

Abstract

The goal of this study was to compare contrast-enhanced T1-weighted Flash and Turbo-Flash sequences with conventional spin-echo sequences as a basis for planning high-precision radiotherapy. A total of 25 consecutive patients with different intracranial tumors and a disrupted blood-brain barrier were studied. T1-weighted Flash, Turbo-Flash and conventional spin-echo images were evaluated after controlled 30-s infusion of 0.1 mmol/kg body weight of Gd-DTPA. The evaluation of the three sequences included the measurement of the spinal- and contrast-to-noise ratios, the visual inspection of the tumors and artifacts, and the measurement of tumor size. The signal- and contrast-to-noise ratios were significantly (P < 0.05-0.01) lower for Flash and Turbo-Flash than for conventional spin-echo sequences. However, visual inspection of the contrast-enhancing tumors revealed in 23 and 24 of 25 lesions on Flash and Turbo-Flash images, respectively, good or very good tumor visibility when compared with conventional spin-echo images with a reduction of imaging time by a factor of 7-8. Flash and Turbo-Flash sequences were more prone to susceptibility artifacts, conventional spin-echo sequences more to pulsation artifacts in the posterior fossa....Continue Reading

Citations

Mar 12, 2013·Neuroradiology·Marc A SchwarzTobias Engelhorn

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