Morphological alterations in the freshwater rotifer Brachionus calyciflorus Pallas 1766 (Rotifera: Monogononta) caused by vinclozolin chronic exposure

Ecotoxicology
Jesús Alvarado-FloresMarcelo Silva-Briano

Abstract

Vinclozolin (VZ) is a dicarboximide fungicide widely used on fruits, vegetables and wines, effective against fungi plagues. In this study we characterized the effects of VZ using a 4-day reproductive chronic assay with the freshwater rotifer Brachionus calyciflorus. The assay included observations of several features of asexual and sexual reproduction. Our results indicate that VZ: (a) increased asexual and sexual reproduction, (b) caused severe abnormality in females and (c) these abnormalities were inherited by sexual and asexual reproduction. At 1.2 mg/L three abnormal females were found out of 457 total females (0.66 %). This low percentage is consistent and reproducible according to further analysis, where we increased the number of replicates and total females exposed to 1.2 mg/L of VZ, and found 18 abnormal females out of 2868 total females (0.63 % abnormality). Interestingly, abnormal females found at 5.6 mg/L VZ exposure, were able to show mating behavior. Our results suggest that VZ behaves as a strong endocrine disruptor whose effects show the characteristic inverted-U-shape exposure concentration response curve regarding the intrinsic population increase and the percentage of abnormalities as endpoints.

References

Feb 1, 1982·The Science of the Total Environment·A R Stebbing
Aug 1, 1997·Endocrine Reviews·J D Graham, C L Clarke
Dec 4, 2001·Bulletin of Environmental Contamination and Toxicology·K I Al-Mughrabi, I M Qrunfleh
Feb 6, 2004·Bulletin of Environmental Contamination and Toxicology·M F El-ShahatF M Alnasir
Jun 16, 2004·Brazilian Journal of Biology = Revista Brasleira De Biologia·L M Elmoor-Loureiro
Jun 4, 2005·Science·Matthew D AnwayMichael K Skinner
Jun 6, 2006·Toxicology and Applied Pharmacology·José-Manuel Molina-MolinaPatrick Balaguer
Jul 14, 2006·Journal of Andrology·Matthew D AnwayMichael K Skinner
Aug 8, 2007·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·Jose L Zavala-AguirreAna L Zamora-Perez
May 20, 2008·Reproductive Toxicology·Steffen SchneiderBennard van Ravenzwaay
Dec 8, 2009·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Michiel B VandegehuchteColin R Janssen
Feb 12, 2010·Archives of Environmental Contamination and Toxicology·M F L LemosA M V M Soares
Jun 16, 2010·Proceedings of the National Academy of Sciences of the United States of America·E Paige StoutJulia Kubanek
Oct 22, 2010·Aquatic Toxicology·Hans-U DahmsJae-Seong Lee
Nov 9, 2010·Reproductive Toxicology·Michael K SkinnerCarlos Guerrero-Bosagna
May 17, 2011·Aquatic Toxicology·Lihua YangZijian Wang

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Citations

Jan 21, 2017·Ecotoxicology·Adriana Aránguiz-Acuña, Pablo Pérez-Portilla
Jun 21, 2017·Environmental Science and Pollution Research International·Carlos Vicente Garza-LeónRoberto Rico-Martínez

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