The reovirus-like particles present in the feces of young pigs and foals with acute enteritis and the virus causing epizootic diarrhea of infant mice were found to be indistinguishable morphologically from each other, from the South African SA. 11 and "O" viruses, and from the rotaviruses of children and calves. The inner capsid layer of each of these viruses reacted seriologically with sera of children, calves, mice, piglets, and foals convalescent from infection with their respective rotaviruses. These sera reacted by immunofluorescence with human, bovine, porcine, and murine rotaviruses, SA.11, and "O" viruses in tissue cultures and with human bovine, procine, nad murine viral antigens by complement fixation and gel diffusion. However, the antisera differed in their ability to react serologically with the outer capsid layer of the viruses investigated and in their ability to neutralize tissue culture-adapted calf virus. These two tests may demonstrate strain or host specificity among rotaviruses. Since the porcine, murine, and equine viruses are closely related serologically to and are morphologically identical to the human and bovine viruses, they should be included in the group of viruses for which the term "rotavirus" has...Continue Reading
New complement-fixation test for the human reovirus-like agent of infantile gastroenteritis. Nebraska calf diarrhea virus used as antigen
Gnotobiotic piglets experimentally infected with neonatal calf diarrhoea reovirus-like agent (Rotavirus)
Virus particles in epithelial cells of duodenal mucosa from children with acute non-bacterial gastroenteritis
Diagnostic electron microscopy of faeces. I. The viral flora of the faeces as seen by electron microscopy
Diagnostic electron microscopy of faeces. II. Acute gastroenteritis associated with reovirus-like particles
Physicochemical and morphological relationships of some arthropod-borne viruses to bluetongue virus--a new taxonomic group. Physiocochemical and serological studies
Reoviruslike agent in stools: association with infantile diarrhea and development of serologic tests
Cell culture adaptation and propagation of a reovirus-like agent of calf diarrhea from a field outbreak in Nebraska
The conglutination phenomenon; further experiments on the importance of the choice of complement when examining antisera for the presence of complement-fixing or complement-absorbing antibodies
The conglutination phenomenon: VI. An experimental investigation of the factors determining the adsorption of complement by an antigen-antiserum mixture
An immunoelectron microscopic and immunofluorescent study on the antigenic relationship between the coronavirus-like agent, CV 777, and several coronaviruses
Rapid detection of rotavirus in stool by latex agglutination: comparison with radioimmunoassay and electron microscopy and clinical evaluation of the test
Comparison of direct electron microscopy and enzyme immunoassay for the detection of rotaviruses in calves, lambs, piglets and foals
Three different forms of tubular structures associated with the replication of bovine rotavirus in a tissue culture system. Brief report
Serological relationships between rotaviruses from different species as studied by complement fixation and neutralization
Antigenic relationships between rotaviruses from different species as studied by neutralization and immunofluorescence
Neutralizing patterns of anti-bovine rotavirus (Lincoln) serum against cytopathic bovine rotaviruses isolated from calves in Japan
Relative prevalence of typical and atypical strains among rotaviruses from diarrheic pigs in conventional swine herds
Infection in piglets with a porcine rotavirus-like virus. Experimental inoculation and ultrastructural examination
First report of an epidemic of diarrhoea in human neonates involving the new rotavirus and biological characteristics of the epidemic virus strain (KMB/R85)
Detection of group C rotavirus in juvenile ferrets (Mustela putorius furo) with diarrhea by reverse transcription polymerase chain reaction: sequencing and analysis of the complete coding region of the VP6 gene
Comparison of a commercial visible reaction disc enzyme immunoassay to a commercial spectrophotometric bead enzyme immunoassay and electron microscopy for the diagnosis of rotavirus in bovines
Vitamin D Alleviates Rotavirus Infection through a Microrna-155-5p Mediated Regulation of the TBK1/IRF3 Signaling Pathway In Vivo and In Vitro
Further biochemical characterization, including the detection of surface glycoproteins, of human, calf, and simian rotaviruses
Subgroups, serotypes, and electrophoretypes of rotavirus isolated from children in Bangui, Central African Republic.
Identification of a group-reactive epitope of group B rotaviruses recognized by monoclonal antibody and application to the development of a sensitive immunoassay for viral characterization.
Concentration of simian rotavirus SA-11 from tap water by membrane filtration and organic flocculation.
Enzyme-linked immunosorbent assays based on polyclonal and monoclonal antibodies for rotavirus detection.
Relative frequency of rotavirus subgroups 1 and 2 in Venezuelan children with gastroenteritis as assayed with monoclonal antibodies.
Antibodies: Complement Activation
The complement system can be activated by antigen-associated antibody. In the classical pathway of complement activation, C1q, C4b, and C3b are all able to bind to the Fc portion of IgG or IgM. Find the latest research on antibodies and complement activation here.
Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.