Morphological and immunohistochemical characterization of interneurons within the rat trigeminal motor nucleus

Neuroscience
Sarah McDavidArlette Kolta

Abstract

Three series of experiments were carried out to characterize interneurons located within the trigeminal motor nucleus of young rats aged 5-24 days. Cholera toxin injections were made bilaterally into the masseter and, sometimes, digastric muscles to label motoneurons. In the first set of experiments, thick slices were taken from the pontine brainstem and cholera toxin-positive and cholera toxin-negative neurons located inside the trigeminal motor nucleus were filled with biocytin through whole-cell recording patch electrodes. Positively identified motoneurons (cholera toxin+) of various shapes and sizes always had a thick, unbranched axon that entered the motor root following a tight zigzag course. Many cholera toxin-negative neurons were also classified as motoneurons after biocytin filling based on this particularity of their axon. These are probably either fusimotor motoneurons or motoneurons supplying other jaw muscles. The cholera toxin-negative neurons classified as interneurons differed markedly from motoneurons in that they had thin, usually branched axons that supplied the ipsilateral reticular region surrounding the trigeminal motor nucleus (peritrigeminal area), the main trigeminal sensory nucleus, the trigeminal mes...Continue Reading

References

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Citations

May 7, 2009·Current Opinion in Otolaryngology & Head and Neck Surgery·Steven M Barlow
Feb 22, 2012·Progress in Neurobiology·Philippe MorquetteArlette Kolta
May 8, 2007·The Journal of Comparative Neurology·Brita RobertsonRéjean Dubuc
Sep 12, 2008·The European Journal of Neuroscience·Sarah McDavidArlette Kolta
Sep 3, 2013·Current Biology : CB·Christian R Burgess, John H Peever
Jun 10, 2011·Journal of Neurophysiology·Peter B Schwarz, John H Peever
Jul 14, 2020·Frontiers in Cellular Neuroscience·Mohammed Slaoui HasnaouiArlette Kolta

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