Morphological characteristics of Lugaro cells in the cerebellar cortex

Neuroscience and Behavioral Physiology
A B Melik-Musyan, V V Fanardzhyan

Abstract

Two types of Lugaro cells were identified in the cat cerebellar cortex using sections impregnated with silver nitrate by the Golgi-Kopsch method; these cells were fusiform and triangular and their bodies were located at different levels in the granular layer. Their processes were directed horizontally, vertically, or obliquely to the axis of the leaf; axons never left the cerebellar cortex. These cells should therefore be regarded as interneurons. The processes of Lugaro cells were very extended, with the result that these cells formed numerous axosomatic and axodendritic contacts with all cerebellar cortical neurons and fibers. The structural and topographical characteristics of Lugaro cells and the features of their contacts with other cells in the cerebellar cortex, taken together with data on their neurotransmitter contents, show that they function as inhibitory interneurons.

Citations

Dec 4, 2019·Frontiers in Molecular Neuroscience·Francesca PrestoriEgidio D'Angelo
May 19, 2007·Brain, Behavior and Evolution·K W S AshwellC R R Watson
Jun 4, 2016·Cerebellum & Ataxias·Anneh Mohammad Gharravi
Sep 22, 2017·PLoS Computational Biology·Shyam Kumar SudhakarErik De Schutter
Jan 9, 2013·Brain, Behavior and Evolution·Busisiwe C MasekoPaul R Manger

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.