PMID: 4995387Apr 1, 1971Paper

Morphological correlates of increased coupling resistance at an electrotonic synapse

The Journal of Cell Biology
G D PappasM V BENNETT

Abstract

Close appositions between axonal membranes are present in the septum between adjacent axonal segments of the septate or lateral giant axons of the crayfish Procambarus. In sections the closely apposed membranes appear separated by a space or gap. The use of lanthanum indicates that there may be structures connecting the apposed membranes. The apparent gap is actually a network of channels continuous with the extracellular space. Adjacent axonal segments are electrotonically coupled at the septa. The coupling resistance is increased by mechanical injury of an axon, immersion in low Cl(-) solutions, and immersion in low Ca(++) solutions, followed by a return to normal physiological solution. Septa at which coupling resistance had been measured were examined in the electron microscope. The induced increases in coupling resistance are associated with separation of the junctional membranes (with the exception of the moderate increases during immersion in low Ca(++) solutions). Schwann cell processes are present between the separated axonal membranes. When nerve cords in low Cl(-) solutions are returned to normal physiological solution, coupling, i.e., electrotonic synapses. A model of an electrotonic synapse is proposed in which twe...Continue Reading

References

May 1, 1970·The Journal of Cell Biology·D A Goodenough, J P Revel
Mar 1, 1970·Journal of the Neurological Sciences·G D Pappas
Apr 1, 1971·The Journal of Cell Biology·Y Asada, M V Bennett
Jul 14, 1966·Annals of the New York Academy of Sciences·G D Pappas, M V Bennett
Oct 1, 1969·Brain Research·M V Bennett
Mar 1, 1970·The Journal of Cell Biology·M V Bennett, J P Trinkaus
Mar 1, 1968·The Journal of General Physiology·L BarrM M Dewey
Mar 1, 1969·The Journal of Cell Biology·M W Brightman, T S Reese
Aug 8, 1969·Science·B W PaytonG D Pappas
Jun 1, 1967·Developmental Biology·W R Loewenstein
Jun 1, 1967·The Journal of Cell Biology·J P Revel, M J Karnovsky
Jun 1, 1968·The Journal of Cell Biology·S Bullivant, W R Loewenstein
May 1, 1963·The Journal of Cell Biology·M G FARQUHAR, G E PALADE
Nov 1, 1961·The Journal of General Physiology·A WATANABE, H GRUNDFEST
May 1, 1965·The Journal of General Physiology·L BARRW BERGER

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Citations

Feb 27, 1999·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·J D Pitts
Aug 1, 1977·The American Journal of Anatomy·R W KenslerM M Dewey
Jan 1, 1979·The American Journal of Anatomy·P R BrinkM M Dewey
Jun 1, 1976·The Anatomical Record·J C Sipe, R Y Moore
Aug 27, 1973·Zeitschrift für Zellforschung und mikroskopische Anatomie·D C Sandeman, S E Luff
Oct 26, 1973·Zeitschrift für Zellforschung und mikroskopische Anatomie·G P DempseyW B Watkins
Jan 1, 1972·Zeitschrift für Zellforschung und mikroskopische Anatomie·F B Krasne, C A Stirling
Jan 1, 1972·Zeitschrift für Zellforschung und mikroskopische Anatomie·C A Stirling
Nov 1, 1974·Journal of Neurocytology·J M Kerns, A Peters
Feb 1, 1975·Journal of Neurocytology·J Günther
Jul 1, 1980·Neuroscience and Behavioral Physiology·M V Motorina
Aug 15, 1973·Experientia·L OrciA E Renold
Dec 29, 1978·The Journal of Membrane Biology·B Rose, R Rick
Dec 1, 1980·In Vitro·J P RevelB Nicholson
Jul 12, 1974·Brain Research·D Mistick
Mar 24, 1978·Brain Research·M R Meyer, G D Bittner
Jan 26, 1988·Brain Research·T A ViancourK R Seshan
Dec 1, 1972·Developmental Biology·M V BennettG D Pappas
Dec 1, 1973·Developmental Biology·J P RevelL L Chang
Jan 1, 1977·Tissue & Cell·W J Larsen
Jan 1, 1982·Progress in Biophysics and Molecular Biology·W C De Mello
Jan 1, 1992·Electron Microscopy Reviews·B Leitch
Dec 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·J P RevelA J Hudspeth
May 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·L A Staehelin
Jul 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·A J Hudspeth
Nov 1, 1985·The Journal of Cell Biology·T M Miller, D A Goodenough
Feb 1, 1972·The Journal of Cell Biology·A R Hand, S Gobel
May 1, 1972·The Journal of Cell Biology·C Sotelo, R Llinás

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