Morphological-Hemodynamic Characteristics of Intracranial Bifurcation Mirror Aneurysms

World Neurosurgery
Jixing FanYing Zhang

Abstract

Many morphological and hemodynamic parameters have been proposed as promising aneurysm rupture status discriminators. Besides, a clear dichotomy between sidewall and bifurcation aneurysms was reported. In this study, we strove to evaluate the contribution of many reported morphological and hemodynamic parameters to retrospective rupture status determination in bifurcation aneurysms independent of patients' characteristics. Computational fluid dynamics were performed on 16 patients with bifurcation mirror aneurysms (MANs). Each pair was divided into ruptured and unruptured groups. The morphological and hemodynamic factors were analyzed and compared. Receiver operating characteristics (ROC) analysis was performed, and the area under the ROC curve (AUC) was calculated for all parameters to quantify the predictability of each index and identify the optimal threshold. Morphological (size, aspect ratio, size ratio, and height-width ratio) and hemodynamic (time-averaged mean wall shear stress [WSSmean], low WSS area [LSA]) parameters reached statistical significance (P < 0.05). Aneurysm irregular shape, oscillatory shear index (OSI), flow stability, inflow concentration, and impingement zone did not achieve significantly statistical d...Continue Reading

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Citations

Feb 18, 2017·AJNR. American Journal of Neuroradiology·R DoddasomayajulaJ R Cebral
Aug 26, 2017·Journal of Neurosurgery·Homajoun MaslehatyAthanasios K Petridis
Jul 2, 2019·Neurosurgical Focus·Mahsa DabaghAmanda Randles
Jul 2, 2019·Neurosurgical Focus·Eva L LeemansCharles B L M Majoie
Jun 18, 2020·Neuropsychiatric Disease and Treatment·Jinlong YuanXinggen Fang
Oct 7, 2017·AJNR. American Journal of Neuroradiology·R DoddasomayajulaJ R Cebral

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