Morphological parameters associated with middle cerebral artery aneurysms

Neurosurgery
Anil CanRose Du

Abstract

Morphological factors contribute to the hemodynamics of the middle cerebral artery (MCA). To identify image-based morphological parameters that correlated with the presence of MCA aneurysms. Image-based anatomic parameters obtained from 110 patients with and without MCA bifurcation aneurysms were evaluated with Slicer, an open-source image analysis software, to generate 3-dimensional models of the aneurysms and surrounding vascular architecture. We examined segment lengths, diameters, and vessel-to-vessel angles of the parent and daughter vessels at the MCA bifurcation. In order to reduce confounding by genetic and clinical risk factors, 2 control groups were selected: group A (the unaffected contralateral side of patients with unilateral MCA bifurcation aneurysms) and group B (patients without intracranial aneurysms or other vascular malformations). Univariate and multivariate analyses were performed to determine statistical significance. One hundred ten patients who were evaluated from 2007 to 2014 were analyzed (73 patients with MCA aneurysms and 37 control patients). Multivariate analysis revealed that a smaller parent artery diameter (group A: odds ratio [OR] 0.20, P < .01, group B: OR 0.23, P < .01) and a larger daughter-...Continue Reading

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Citations

Jul 16, 2020·Scientific Reports·Jian ZhangRose Du
Jun 20, 2020·AJNR. American Journal of Neuroradiology·Z HuangF H Chen
Jan 23, 2021·Journal of Neurointerventional Surgery·Jian ZhangRose Du
Jan 30, 2021·Scientific Reports·Jian ZhangRose Du

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