Morphological properties of intracellularly labeled layer I neurons in rat neocortex

The Journal of Comparative Neurology
F M Zhou, J J Hablitz

Abstract

The morphology of neurons in layer I of rat neocortex, including Cajal-Retzius (CR) cells, was studied by using intracellular biocytin staining in brain slices obtained from rats during the first 22 postnatal days. Within the first postnatal week, horizontal bipolar neurons or CR cells were prominent in layer I. Typically, CR cells had one main dendrite and one axon originating from opposite poles of the somata. Even though the main dendrites and axons could be quite long, complex dendritic or axonal arbors were not observed. Starting around postnatal day 6 (PN 6), CR cells were less frequently observed. From PN 10 to PN 21, nonpyramidal neurons with diverse morphologies became the main neuronal component in layer I. The somata of layer I nonpyramidal neurons were quite variable in size and shape. Dendrites were smooth or sparsely spiny, and the dendritic trees were mainly restricted to layer I, covering an area with a diameter of about 200 microns. Axon collaterals of these cells formed elaborate arbors with diameters of around 700 microns in layer I and extending, in many cases, to layer II/III and even layer IV. This extensive axonal plexus provides a rich anatomical base on which layer I neurons, functioning as local circui...Continue Reading

References

Nov 1, 1977·The Journal of Comparative Neurology·R BradfordA R Lieberman
Apr 22, 1992·Proceedings. Biological Sciences·J C AndersonC W Picanço-Diniz
Sep 1, 1990·The Journal of Comparative Neurology·M Marín-Padilla
Jan 1, 1986·Anatomy and Embryology·F Valverde, M V Facal-Valverde
Apr 15, 1989·The Journal of Comparative Neurology·K A MartinV Alones
Jan 1, 1988·Experimental Brain Research·M FonsecaA Fairén
Jun 1, 1987·The Journal of Comparative Neurology·Z F KisvardayP Somogyi
Nov 15, 1985·The Journal of Comparative Neurology·C G Van Eden, H B Uylings
Jun 1, 1973·The Journal of Comparative Neurology·D W Vaughan, A Peters
Sep 10, 1984·The Journal of Comparative Neurology·G Meyer, R Ferres-Torres
Jun 1, 1982·Journal of Neurocytology·S M Edmunds, J G Parnavelas
May 15, 1994·The Journal of Comparative Neurology·J Li, H D Schwark
Jun 15, 1994·The Journal of Comparative Neurology·J J PrietoJ A Winer
Jun 15, 1994·The Journal of Comparative Neurology·J J PrietoJ A Winer
Jan 22, 1994·The Journal of Comparative Neurology·C BeaulieuC Crevier
Aug 1, 1996·Journal of Neurophysiology·F M Zhou, J J Hablitz
Aug 1, 1996·Journal of Neurophysiology·F M Zhou, J J Hablitz
Dec 1, 1961·The Journal of Comparative Neurology·C R NOBACK, D P PURPURA

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Citations

Jul 1, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Elliott B MerriamMatthew I Banks
Jan 16, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Eunice Y Yuen, Zhen Yan
Dec 27, 2018·The European Journal of Neuroscience·Ying-Wan Lam, S Murray Sherman
Dec 13, 2005·Journal of Neurophysiology·Susanta BandyopadhyayJohn J Hablitz
Nov 18, 2006·Journal of Neurophysiology·Dan ShlosbergRony Azouz
Feb 15, 2018·Frontiers in Cellular Neuroscience·Andrew S Bohannon, John J Hablitz
Jul 19, 2000·Journal of Neurophysiology·R S DammermanA R Kriegstein
Dec 14, 2011·Nature·Johannes J LetzkusAndreas Lüthi
Nov 14, 1997·Journal of Neurophysiology·F M Zhou, J J Hablitz
Sep 3, 2002·Journal of Neurophysiology·Elodie ChristopheEtienne Audinat
May 18, 2020·International Journal of Molecular Sciences·Kai K KummerMichaela Kress
Dec 22, 1999·Journal of Neurophysiology·F M Zhou, J J Hablitz
Dec 4, 2001·Journal of Neurophysiology·C Gonzalez-Islas, J J Hablitz
Oct 23, 1997·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Y Ikeda, T Terashima
Aug 30, 2012·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·D V V SantosM Da Silva Filho
Oct 28, 2006·Cerebral Cortex·Isabelle FérézouBertrand Lambolez
Sep 21, 2004·Nature Reviews. Neuroscience·Henry MarkramCaizhi Wu
Oct 9, 1999·Epilepsy Research·K M JacobsD A Prince
Mar 18, 2021·Annual Review of Neuroscience·Benjamin SchumanBernardo Rudy

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