PMID: 10972940Sep 6, 2000Paper

Morphology and topographical organization of the retrospleniocollicular connection: a pathway to relay contextual information from the environment to the superior colliculus

The Journal of Comparative Neurology
Gontzal García del CañoLuis Martínez-Millán

Abstract

The retrospleniocollicular connection is of interest because it constitutes one link between the limbic system, which is considered the anatomical substrate of emotional experience, and the superior colliculus (SC), which mediates approach and avoidance behavior. The morphology, topography, and origin of the retrospleniocollicular connections were studied by using anterograde [biotinylated dextranamine 10,000 (BDA)] and retrograde [Fluoro-Gold (FG)] tracers. After BDA injections involving retrosplenial granular and agranular cortices, terminal fibers innervating all collicular layers except stratum griseum superficiale were found throughout nearly the entire colliculi. Axons branched within restricted portions of the dorsoventral collicular axis with variable morphologies, suggesting functional heterogeneity. Terminal fields originating in anterior and posterior regions of the retrosplenial cortex were preferentially distributed in laterodorsal and medioventral collicular regions, respectively, but there were also large, densely innervated regions in which the terminal fields overlapped. FG injections in the SC confirmed the retrospleniocollicular topography and demonstrated that this connection originated from layer V pyramida...Continue Reading

References

Apr 1, 1977·Journal of Comparative and Physiological Psychology·M GabrielS E Saltwick
Oct 1, 1977·Experimental Neurology·R C Meibach, A Siegel
Jan 1, 1992·Canadian Journal of Physiology and Pharmacology·R A Swanson
Oct 15, 1992·The Journal of Comparative Neurology·T Van Groen, J M Wyss
Nov 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·R B Illing
Jan 8, 1992·The Journal of Comparative Neurology·T Van Groen, J M Wyss
Dec 11, 1990·Neuroscience Letters·R B IllingW B Spatz
Oct 22, 1990·The Journal of Comparative Neurology·T Van Groen, J M Wyss
Nov 1, 1986·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·H TagoT Maeda
Apr 1, 1989·Trends in Neurosciences·P DeanG W Westby
Apr 1, 1989·Behavioural Brain Research·R J Sutherland, A J Rodriguez
May 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·S A Bloomfield, S M Sherman
Aug 1, 1987·Brain Research Bulletin·R L ReepR T Watson
Jan 1, 1989·Experimental Brain Research·A L MarkowskaD Gaffan
Jan 1, 1988·Experimental Brain Research·D P NorthmoreG E Schneider
Dec 8, 1986·The Journal of Comparative Neurology·K Sripanidkulchai, J M Wyss
Feb 1, 1969·Brain Research·V B Domesick
Jul 23, 1971·Brain Research·P L ParmeggianiP L Lenzi
Feb 22, 1974·Brain Research·P L ParmeggianiA Azzaroni
May 1, 1973·The Journal of Comparative Neurology·S Locke, C Kerr
Sep 1, 1973·Journal of Neurophysiology·M Segal
May 10, 1983·The Journal of Comparative Neurology·B A Vogt, M W Miller

Citations

Jun 6, 2008·Brain Research·Armando CardosoNikolai V Lukoyanov
Nov 26, 2009·Neuroscience·I C Mundiñano, Luis Martínez-Millán
Jun 13, 2018·The Journal of Comparative Neurology·Marie BarbierPierre-Yves Risold
Oct 19, 2006·The Journal of Comparative Neurology·Gontzal García del CañoLuis Martínez-Millán
Jun 23, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Claire Allison, Judith A Pratt

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