PMID: 8580661Oct 1, 1995Paper

Morphology in intracytoplasmic sperm injection: preliminary results

Journal of Assisted Reproduction and Genetics
W KüpkerK Diedrich

Abstract

Direct intracytoplasmic sperm injection (ICSI) is a successful treatment of severe male subfertility. Conventional in vitro fertilization shows poor pregnancy rates especially in cases of severe teratozoospermia. The objective was to determine if severe morphological defects of spermatozoa in oligoasthenoteratozoospermia (OAT) have any impact on the fertilization process in ICSI and if there are any specific morphological characteristics in nonfertilized oocytes after the ICSI procedure. Ejaculates and nonfertilized oocytes were investigated by electron microscopy. The lack of intracytoplasmic sperm-oocyte interaction, not severe sperm defects, displays the most critical role in the fertilization process. Clinical data with fertilization rates of 66% and pregnancy rates of 23.3% confirm the fertilization capacity of severely

References

Dec 1, 1986·Fertility and Sterility·T F KrugerK Smith
Aug 1, 1994·Human Reproduction·W OmbeletT Kruger
May 1, 1993·Geburtshilfe und Frauenheilkunde·S AlpüstünD Krebs

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Citations

Apr 3, 2013·Journal of Assisted Reproduction and Genetics·Edson BorgesAssumpto Iaconelli
Feb 13, 1999·Fertility and Sterility·K CoetzeeC J Lombard
Dec 1, 1999·European Journal of Obstetrics, Gynecology, and Reproductive Biology·M LudwigK Diedrich
Jun 8, 2012·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Rita de Cássia S FigueiraEdson Borges
Nov 15, 2011·Fertility and Sterility·Daniela Paes de Almeida Ferreira BragaEdson Borges
Jun 24, 2006·Reproductive Biomedicine Online·Jan TesarikCarmen Mendoza
Oct 1, 1996·The Journal of Urology·V Mak, K A Jarvi
Jul 16, 2009·Drug Metabolism Reviews·Mark LovernJean-Baptiste Watelet
Aug 21, 2020·Reproductive Biology and Endocrinology : RB&E·Domenico BaldiniDamiano Vizziello

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