Jan 1, 1977

Morphology of cirrhosis of the liver in hepato-cerebral dystrophy (according to needle biopsy findings)

Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova
V A MakarovaB I Shulutko

Abstract

The paper presents data of a luminous microscopy of the liver that were obtained by aspiration biopsy in 23 patients with hepato-cerebral dystrophy in comparison with 25 patients with cirrhosis of a hereditary etiology. In the majority of the cases (21 from 23) the method of puncture biopsy of the liver provides the diagnosis of cirrhosis in hepatocerebral dystrophy. The complex use of histochemical methods and especially staining for reticuline and cuprum significantly increases its informativeness. In 15 of 28 patients cirrhosis was of a mixed character (postnecrotic and portal), in 5 patients--postnecrotic and in a preneurologic stage it corresponded to the initial features of portal cirrhosis. The damage of the liver precedes the brain damage and is connected with an excessive accumulation of cuprum in it, the amount of which is significantly higher (559 +/- 89 mkg/g of dry weight) in the patients with hepato-cerebral dystrophy in comparison with the patients with cirrhosis of some other etiology (111.0 +/- 19.0 mkg/g of a dry weight).

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Hepatopulmonary Syndrome
Science of Morphology
Cirrhosis
Brain
Hypertension, Portal
Liver Glycogen
Puncture Biopsy
Fine Needle Aspiration Biopsy
Etiology
Lipofuscin

About this Paper

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Bone Marrow Neoplasms

Bone Marrow Neoplasms are cancers that occur in the bone marrow. Discover the latest research on Bone Marrow Neoplasms here.

IGA Glomerulonephritis

IgA glomerulonephritis is a chronic form of glomerulonephritis characterized by deposits of predominantly Iimmunoglobin A in the mesangial area. Discover the latest research on IgA glomerulonephritis here.

Cryogenic Electron Microscopy

Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

LRRK2 & Immunity During Infection

Mutations in the LRRK2 gene are a risk-factor for developing Parkinson’s disease. However, LRRK2 has been shown to function as a central regulator of vesicular trafficking, infection, immunity, and inflammation. Here is the latest research on the role of this kinase on immunity during infection.

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

Meningococcal Myelitis

Meningococcal myelitis is characterized by inflammation and myelin damage to the meninges and spinal cord. Discover the latest research on meningococcal myelitis here.

Alzheimer's Disease: MS4A

Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. Here is the latest research.

Related Papers

Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova
V A Makarova, A V Reiskanen
Journal of Clinical Gastroenterology
A C BernthalJ A Payne
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova
V A Makarova
© 2020 Meta ULC. All rights reserved