Morphology of intraductal papillary neoplasm of the bile ducts: radiologic-pathologic correlation

Abdominal Imaging
Heejung KimRichard Baron

Abstract

Intraductal papillary neoplasm of the bile duct (IPN-B) is known as a premalignant lesion of invasive cholangiocarcinoma. The purpose of this study was for radiologic-pathologic correlation of morphologic features of IPN-B and to correlate the subclassifications with biological behavior in regard to the bile duct wall invasion. A pathologist classified gross morphology of 75 cases (44 men and 31 women, age range, 39-85) of histopathologically proven IPN-B into polypoid, cast-like, superficial-spreading, and cyst-forming type. Preoperative images were retrospectively reviewed by two observers independently and classified the gross appearance of intraductal tumors into the four types. The pathologist classified macroscopic appearances of 75 cases of IPN-B into polypoid type in 26, cast-like intraductal growth in 17, superficial-spreading growth in 21, and cyst-forming type in 11. Two observers classified image findings in accordance with pathologist's classification in 58 and 57 (77% and 76%) among the 75 cases of IPN-B, respectively; 18 and 19 of 26 cases of polypoid type, 14 and 14 of 17 cases of cast-like growth type, 16 and 19 of 21 cases of superficial-spreading type, 10 and 5 of 11 cases of cyst-forming type, respectively. ...Continue Reading

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Citations

Dec 8, 2011·World Journal of Gastroenterology : WJG·Nam Kyung LeeDae Hwan Kang
May 23, 2012·Annals of Nuclear Medicine·Aisheng DongChangjing Zuo
Apr 10, 2018·AJR. American Journal of Roentgenology·Hyo Jung ParkMoon-Gyu Lee
Nov 16, 2017·European Radiology·Shihong YingWenbo Xiao
Aug 18, 2020·Hepatic Medicine : Evidence and Research·Narong KhuntikeoRichard R A Syms
Apr 14, 2020·Hepatic Medicine : Evidence and Research·Narong KhuntikeoRichard R A Syms
Jun 17, 2021·Seminars in Ultrasound, CT, and MR·Winnie A MarSenta M Berggruen
Jul 24, 2021·Pathologica·Samantha SarcognatoMaria Guido
Oct 2, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Matthew H LeePerry J Pickhardt

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