PMID: 7534470Jan 1, 1994

Morphology of sweat glands in determining time of death

International Journal of Legal Medicine
M CingolaniS D Ferrara

Abstract

This study demonstrates post-mortem autolytic alterations in the skin at cellular and subcellular levels and identifies parameters which may assist in determining the time of death in the first few hours post-mortem. Serial skin samples from the ventral surface of the arm were taken at intervals of 3, 6, 9 and 12 h after death in 29 subjects of various ages, with no signs of skin disease; causes of death were various. Three types of tests were performed: cytochemical (hematoxylin-eosin and alcian-PAS), immunohistochemical (S-100, CEA, Cytokeratin, ASM) and ultrastructural (electron microscopy). Electron microscopy proved useful for identifying transformations which were found to be specific for each chronological step considered: reduction of intracellular glycogen in clear cells and reduction of secretory granules in dark cells are typical signs of the first stage (3 h) after death; mitochondrial dilatation and rarefaction of cristae in clear and dark cells are typical of the second stage (6 h); rarefaction of microvilli in dark and clear cells is a sign of the last stage (12 h). Cytochemistry and immunohistochemistry supply useful information--not for all the chronological stage considered here, but for individual phases (3 h...Continue Reading

References

Jan 1, 1977·Reviews of Physiology, Biochemistry and Pharmacology·K Sato
Nov 1, 1976·Forensic Science·T Suzuki
Jan 1, 1990·Methods in Enzymology·K Sato, F Sato
Sep 1, 1983·The American Journal of Physiology·K Sato, F Sato
Jun 1, 1993·The American Journal of Forensic Medicine and Pathology·J I Coe

Citations

Jun 8, 2000·Forensic Science International : Synergy·F WehnerJ Subke
Oct 24, 2001·Forensic Science International : Synergy·F WehnerJ Subke
Jan 17, 2002·Forensic Science International : Synergy·F WehnerJ Subke
Jan 22, 2000·Forensic Science International : Synergy·F WehnerJ Subke
Jan 23, 2002·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Peter PietzonkaHans P Merkle
May 4, 2013·Legal Medicine·Shiwei MaoZhenyuan Wang
Sep 6, 2011·Science & Justice : Journal of the Forensic Science Society·Shiwei MaoZhenyuan Wang
Oct 14, 2005·Legal Medicine·Takaki IshikawaHitoshi Maeda
Nov 6, 2015·Journal of Applied Oral Science : Revista FOB·Luciana Reis Azevedo-AlanisJosé Humberto Damante
Nov 19, 2010·Journal of Applied Oral Science : Revista FOB·Leticia Rodrigues NeryJosé Humberto Damante
Sep 8, 2011·The American Journal of Forensic Medicine and Pathology·Rajesh V BardaleAshutosh Y Deshmukh

Related Concepts

Isoactin
Autolysis
Carcinoembryonic Antigen
Plasma Membrane
Protoplasm
Cytochemistry
Immunocytochemistry
Keratin-Associated Proteins
Electron Microscopy
Mitochondria

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