PMID: 43878Jan 1, 1979

Morphology of the antibody response to pneumococcal polysaccharide in mice

Journal of hygiene, epidemiology, microbiology, and immunology
I Hajdu

Abstract

In the course of an antibody immune response to pneumococcal polysaccharide - type III (S III) in mice a slight increase was observed in the proportion of plasma cells among the antibody-producing cells, reaching its peak at the time of decline of this reaction. On the basis of ultrastructural resemblance of these plasma cells to primitive reticular cells and in view of other specificities of the immunological response to S III antigen, the author presumes direct reticular origin of anti-S III antibody-producing plasma cells.

Related Concepts

Antibodies, Bacterial
Antibody-Secreting Cells
Hemolytic Plaque Technique
Lymphoid Cells
Plasma Cells
Polysaccharides, Bacterial
Spleen
Streptococcus pneumoniae

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