PMID: 6166638Jun 1, 1981Paper

Morphometric differences between urothelial cells in voided urine of patients with grade I and grade II bladder tumours

Journal of Clinical Pathology
M E BoonE C Ooms

Abstract

The morphometric differences between the urothelial cells in the voided urine of 24 patients with grade I and grade II bladder tumours were measured. In both wet-fixed Papanicolaou-stained smears as in air-dried Giemsa-stained preparations, the cells in the grade I tumours are larger and have more pronounced anisocytosis and a smaller nucleus to cytoplasm area (N/C) ratio. Although absolute dimensions of cells and nuclei in the two preparatory technique differ significantly, the average N/C ratios are similar. In both methods almost all grade I tumours have average N/C cell size ratios of less than 0.6 and grade II tumours more than 0.6. Morphometrically urothelial cells could not be distinguished from cells exfoliated from grade I bladder tumours. The results indicate that it is feasible to classify bladder tumours using the morphometric values of the exfoliated urothelial cells alone.

Citations

Jan 1, 1982·Virchows Archiv. A, Pathological Anatomy and Histology·M E BoonJ P Baak
Jan 1, 1984·Virchows Archiv. A, Pathological Anatomy and Histopathology·K HelanderG Holmberg
Jan 1, 1988·Virchows Archiv. A, Pathological Anatomy and Histopathology·H G van der PoelE C Ooms
Jan 1, 1990·Virchows Archiv. A, Pathological Anatomy and Histopathology·H G van der PoelA Wijsman-Grootendorst
May 7, 2014·The Indian Journal of Surgery·Asim Kumar MannaDiptendra Kumar Sarkar
Feb 1, 1991·Japanese Journal of Cancer Research : Gann·T Ishido, K Nakamura
Jan 1, 1985·Critical Reviews in Toxicology·P H Bach, J W Bridges
Jan 1, 1985·CRC Critical Reviews in Toxicology·P H Bach, J W Bridges
Jul 1, 1992·The Journal of Urology·H G van der PoelJ A Schalken

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