Morphometry of the amygdala in schizophrenia and psychotic bipolar disorder

Schizophrenia Research
Pamela B MahonJ Tilak Ratnanather

Abstract

Volumetric studies suggest smaller amygdalae in subjects with schizophrenia (SZ) than with bipolar disorder (BP). We use morphometry to identify subregions of amygdala differentially affected in SZ and psychotic BP. Based on template centered population analysis, the shape of the amygdala in psychotic BP differs from SZ (pleft=0.044, pright=0.042). Using a high-field 7 T atlas, the bilateral basolateral, basomedial and centromedial subregions and the right lateral subregion were significantly atrophied in SZ compared to psychotic BP (p<0.02). These results suggest that change in shape of amygdala may represent a morphologic feature distinguishing SZ from psychotic BP.

References

Dec 16, 2003·Cognitive, Affective & Behavioral Neuroscience·Fionnuala C MurphyAndrew D Lawrence
Jun 29, 2004·NeuroImage·F SégonneB Fischl
Jan 18, 2006·Computer Methods and Programs in Biomedicine·Hangyi JiangSusumu Mori
Apr 11, 2006·Harvard Review of Psychiatry·James B Potash
Mar 5, 2008·Neuroscience and Biobehavioral Reviews·Karine SergerieJorge L Armony
Apr 8, 2009·Neuroscience Letters·P Fusar-PoliP L Politi
Feb 2, 2010·The British Journal of Psychiatry : the Journal of Mental Science·Nick Craddock, Michael J Owen
Jun 23, 2010·Bipolar Disorders·Daniel MamahDeanna M Barch
Feb 16, 2011·Bipolar Disorders·Chi-Hua ChenEd T Bullmore
Oct 14, 2011·Biological Psychiatry·Stephan F TaylorTimothy D Johnson
Nov 22, 2011·Journal of Psychiatric Research·Emilio VareaJuan Nacher
May 9, 2012·Schizophrenia Research·Pamela Belmonte MahonPatrick E Barta
Sep 10, 2013·Schizophrenia Research·J Tilak RatnanatherPatrick E Barta
Sep 17, 2013·Bipolar Disorders·Ryan KelleyAllan L Reiss

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Citations

Jan 29, 2016·Human Brain Mapping·Tamar GreenAllan L Reiss
Mar 16, 2016·NeuroImage. Clinical·Daniel MamahLei Wang
Mar 13, 2016·Psychiatry and Clinical Neurosciences·Massimiliano BuoliA Carlo Altamura
Nov 24, 2018·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Hamid M AbdolmalekySam Thiagalingam
Dec 16, 2018·NeuroImage. Clinical·Sue KulasonUNKNOWN Alzheimer's Disease Neuroimaging Initiative
Jan 23, 2021·Schizophrenia Bulletin·Claudia BarthIngrid Agartz
Mar 6, 2021·Frontiers in Psychiatry·Thomas L AtheyPamela B Mahon
Apr 9, 2021·Scientific Reports·Hongge LuoShuping Tan

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