Mortality and cancer incidence in a copper-zinc cohort

Workplace Health & Safety
N Lightfoot, C Berriault

Abstract

Previous studies of copper-zinc workers have primarily observed significant increases in lung and other respiratory cancers. This study concurrently examined cancer incidence and cause-specific mortality for a cohort of workers at a copper-zinc producer in Ontario, Canada, from 1964 to 2005. Significant elevations in lung cancer incidence were observed for males in the overall cohort (standardized incidence ratio [SIR] = 124, 95% confidence interval [CI] = 102-150) and for surface mine (SIR = 272, 95% CI = 124-517), concentrator (SIR = 191, 95% CI = 102-327), and central maintenance (SIR = 214, 95% CI = 125-343) employees. Significant elevations of non-Hodgkin's lymphoma incidence were observed for male underground mine employees (SIR = 232, 95% CI = 111-426). Occupational etiology cannot be ascertained with the current exploratory study design. Future studies could (1) incorporate exposure assessment for subgroups within the existing cohort and (2) determine the efficacy of wellness programs in partnership with the local health unit.

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Citations

Jun 9, 2016·Archives of Environmental & Occupational Health·Nancy E LightfootBruce R Conard
May 31, 2018·Acta Neurologica Scandinavica·G CeaA Stuardo
Mar 25, 2018·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Thorsten FrenzelPeter Bannas
Mar 29, 2019·International Journal of Environmental Research and Public Health·Lusine YaghjyanLiang Mao
Nov 18, 2018·International Journal of Cancer. Journal International Du Cancer·Corina S RueeggMarit B Veierød
May 31, 2012·British Journal of Cancer·T Y O YangUNKNOWN Million Women Study
Oct 29, 2015·The British Journal of Nutrition·Nitin ShivappaMarta Rossi
Apr 1, 2016·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Martin LovecekRoman Havlik

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