Mortality and Medical Comorbidity in the Severely Mentally Ill

Deutsches Ärzteblatt International
Frank SchneiderFrank Jacobi

Abstract

Mentally ill patients die on average 10 years earlier than the general population, largely due to general medical disorders. This study is the first to explore in a large German sample the prevalence, mortality, and medical comorbidity in pa- tients with severe mental illness (SMI). The patients were affected by borderline personality disorder (BPD), psychotic disorders, bipolar disorder, or severe unipolar depression. Our database consists of billing data from all adults with statutory health insurance in Germany. Twelve-month administrative SMI prevalence and medical comorbidity were estimated using cross-sectional data from 2016 (age ≥ 18; N = 59 561 310). Two-year mortality was established longitudinally in a randomly selected subset of the billing data (most recent mortality information available for 2012 to 2014; 2012: n = 15 590 107). Severe unipolar depression had the highest prevalence (2.01%), followed by psychotic disorders (1.25%), BPD (0.34%), and bipolar disorder (0.29%). While the prevalence of malignant neoplasms showed moderate deviations from reference values [severe unipolar depression: OR = 1.30 (95% CI = 1.29; 1.31), BPD: OR = 1.11 (1.09; 1.14), psychotic dis- orders: OR = 0.90 (0.89; 0.90), bipolar disorde...Continue Reading

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Citations

May 20, 2020·Current Opinion in Psychiatry·Uta GühneThomas Becker
Jul 24, 2020·Current Opinion in Supportive and Palliative Care·Guy PeryerMorag Farquhar
Sep 20, 2020·Perspectives in Psychiatric Care·Ozge Sukut, Cemile Hürrem Ayhan Balik
May 12, 2020·Frontiers in Psychiatry·Sarah Kittel-SchneiderAndreas Reif
Jan 7, 2021·Molecular Neurobiology·Roberta Eduarda GrolliZuleide Maria Ignácio
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Nov 12, 2019·Deutsches Ärzteblatt International·Frank Schneider
Dec 7, 2021·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Fabian StreitKlaus Berger

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