PMID: 25735333Mar 5, 2015Paper

Mortality determinants in colorectal cancer patients at different grades: a prospective, cohort study in Iran

Asian Pacific Journal of Cancer Prevention : APJCP
Ali AhmadiMohamad Amin Pourhoseingholi

Abstract

Colorectal cancer (CRC) is an important cause of mortality and morbidity in many communities worldwide. This population based study was conducted to assess determinants of colorectal mortality in Iranian patients. A cohort of 1,127 cases of confirmed colorectal cancer registered in a population based registry covering 10 referral hospital in Tehran, Iran, were followed for five years. Information about tumor characteristics, smoking status and family history were collected at base line and survival status were followed every six months by contacting patient or next of kin (if patients died during the follow-up). The cause of death for each case was validated by verbal autopsy and referring to patient medical records at the time of death. The data were analyzed by Stata software using univariate and multivariate analysis (Cox regression). In building the model a p value of less than 5% was considered as significant. The age at diagnosis was 53.5±14 years. Sixty one percent were male. Colorectal mortality among the patients was 96.9 person-years among men and 83 person-years among women. Seventy five percent of patients lived for 2.72 years, 50% for 5.83, and 25% for 13 years after the diagnosis of colorectal cancer. The age at d...Continue Reading

References

Apr 6, 2004·CA: a Cancer Journal for Clinicians·Elizabeth WardMichael Thun
May 21, 2004·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M Ponz de LeonL Roncucci
Apr 28, 2005·American Journal of Public Health·Mona JeffreysTony Blakely
Nov 1, 2005·The Lancet Oncology·Joseph J Y SungUNKNOWN Asia Pacific Working Group on Colorectal Cancer
Jul 13, 2006·Cancer·Jeannette Jackson-ThompsonCarol Friedman
Sep 13, 2007·Journal of the National Cancer Institute·Jessica D AlbanoMichael J Thun
Jul 31, 2010·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Michael HoffmeisterHermann Brenner
Feb 8, 2011·CA: a Cancer Journal for Clinicians·Ahmedin JemalDavid Forman
Sep 4, 2012·Asian Pacific Journal of Cancer Prevention : APJCP·Azadeh SafaeeMohammad Reza Zali

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Citations

Jul 23, 2016·AJR. American Journal of Roentgenology·Charles MarcusRathan M Subramaniam
Dec 3, 2017·Best Practice & Research. Clinical Gastroenterology·Úna C McMenaminAndrew T Kunzmann

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