Mortality from Crohn's disease and ulcerative colitis in England-Wales and the U.S. from 1950 to 1983

Diseases of the Colon and Rectum
A Sonnenberg

Abstract

As the etiology of inflammatory bowel disease remains unknown, studies of its time trends may provide clues to understanding the underlying mechanisms. This study examines mortality from Crohn's disease and ulcerative colitis in England and Wales and the U.S. during the period 1950 to 1983. Mortality from Crohn's disease and ulcerative colitis changed in both countries similarly. The death rates from Crohn's disease increased until 1970 to 1974 and decreased thereafter. The death rates from ulcerative colitis decreased throughout the observation period. Similar time trends occurred in men and women, and in the U.S. in whites and nonwhites. In the U.S., the death rates from both diseases were twofold higher in whites than nonwhites. The temporal changes suggest that mortality from inflammatory bowel disease is affected by exogenous factors and that these factors are different for Crohn's disease than for ulcerative colitis. These factors seem to have changed similarly in England and in the U.S.

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Citations

Apr 1, 1989·Digestive Diseases and Sciences·A Sonnenberg, T R Koch
Nov 1, 1989·Digestive Diseases and Sciences·A Sonnenberg, T R Koch
Dec 1, 1986·Diseases of the Colon and Rectum·A Sonnenberg
Jan 1, 1982·Irish Journal of Medical Science·S F HabbaJ S Doyle
Mar 1, 1997·Baillière's Clinical Gastroenterology·W Selby
Sep 26, 1991·The New England Journal of Medicine·D K Podolsky
Sep 10, 2005·Gut·F L WoltersUNKNOWN European Collaborative study group on Inflammatory Bowel Disease (EC-IBD)
Jan 27, 2010·World Journal of Gastroenterology : WJG·Lori A ButtonJohn G Williams
Dec 23, 2008·Scandinavian Journal of Gastroenterology·Inger Camilla SolbergUNKNOWN IBSEN Study Group
Feb 24, 2001·Scandinavian Journal of Gastroenterology·F FarrokhyarE J Irvine
Apr 1, 1996·Scandinavian Journal of Gastroenterology·M CottoneL Pagliaro
Aug 25, 2009·Gastroenterology Clinics of North America·Michael F Picco, John R Cangemi
Oct 17, 2008·Annals of Epidemiology·Amnon Sonnenberg
Sep 2, 2004·Alimentary Pharmacology & Therapeutics·F L WoltersR W Stockbrügger
Mar 10, 2001·The American Journal of Gastroenterology·F FarrokhyarE J Irvine
Aug 7, 1995·The Medical Journal of Australia·J M AndrewsK Goulston

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