Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde.

Journal of the National Cancer Institute
Michael HauptmannRichard B Hayes

Abstract

Excess mortality from lymphohematopoietic malignancies, in particular myeloid leukemia, and brain cancer has been found in surveys of anatomists, pathologists, and funeral industry workers, all of whom may have worked with formaldehyde. We investigated the relation of mortality to work practices and formaldehyde exposure levels among these professionals to address cancer risk in the funeral industry. Professionals employed in the funeral industry who died between January 1, 1960, and January 1, 1986, from lymphohematopoietic malignancies (n = 168) or brain tumors (n = 48) (ie, case subjects) were compared with deceased matched control subjects (n = 265) with regard to lifetime work practices and exposures in the funeral industry, which were obtained by interviews with next of kin and coworkers, and to estimated levels of formaldehyde exposure. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated by use of logistic regression. All statistical tests were two-sided. Mortality from myeloid leukemia increased statistically significantly with increasing number of years of embalming (P for trend = .020) and with increasing peak formaldehyde exposure (P for trend = .036). Compared with subjects who performed fewer than ...Continue Reading

References

Nov 8, 1975·British Medical Journal·J M Harrington, H S Shannon
Jan 1, 1991·American Journal of Industrial Medicine·A HallT C Aw
Aug 15, 1991·American Journal of Epidemiology·L M BrownL Burmeister
Jan 1, 1990·American Journal of Industrial Medicine·R B HayesH Mahar
Dec 1, 1990·Scandinavian Journal of Work, Environment & Health·A BlairC Shy
Mar 1, 1986·American Journal of Epidemiology·M L Lerchen, J M Samet
Nov 1, 1968·Health Physics·J S LaughlinJ F Duplissey
Oct 1, 1984·Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association·R J LevineL K Shaw
Mar 1, 1984·American Industrial Hygiene Association Journal·T M WilliamsP B Blunden
May 1, 1984·British Journal of Industrial Medicine·J M Harrington, D Oakes
Apr 15, 1983·International Journal of Cancer. Journal International Du Cancer·J Walrath, J F Fraumeni
Mar 1, 1996·American Industrial Hygiene Association Journal·R W HornungR B Hayes
Apr 25, 2000·Journal of Occupational and Environmental Medicine·J P FryzekJ K McLaughlin
Nov 6, 2003·Journal of the National Cancer Institute·David CoggonKeith T Palmer
Feb 27, 2004·Occupational and Environmental Medicine·L E PinkertonL T Stayner
Jun 12, 2004·American Journal of Epidemiology·Michael HauptmannAaron Blair
Sep 24, 2004·The Lancet Oncology·Vincent CoglianoUNKNOWN WHO International Agency for Research on Cancer
Sep 29, 2004·Regulatory Toxicology and Pharmacology : RTP·Henry d'A Heck, Mercedes Casanova
Aug 5, 2008·Mutation Research·Luoping ZhangMartyn T Smith
May 14, 2009·Journal of the National Cancer Institute·Laura E Beane FreemanMichael Hauptmann

❮ Previous
Next ❯

Citations

May 15, 2010·Archives of Toxicology·Gunnar Damgård Nielsen, Peder Wolkoff
Nov 28, 2012·Archives of Toxicology·Gunnar Damgård NielsenPeder Wolkoff
Sep 9, 2010·Journal of the National Cancer Institute·Philip ColeJack S Mandel
Feb 16, 2011·Journal of the National Cancer Institute·Niels HammerHanno Steinke
Dec 18, 2010·Toxicological Sciences : an Official Journal of the Society of Toxicology·James A SwenbergThomas B Starr
Apr 5, 2012·Toxicological Sciences : an Official Journal of the Society of Toxicology·Stefanie KuehnerGünter Speit
Apr 12, 2013·Occupational and Environmental Medicine·Fatemeh Saberi HosnijehRoel Vermeulen
Dec 12, 2012·BMC Public Health·Florian Rudolf FritzscheAntony Stewart
May 24, 2013·Journal of Occupational Medicine and Toxicology·Ioannis PolychronakisAthena Linos
May 24, 2014·Journal of Occupational Medicine and Toxicology·Gary M MarshJames Morel Symons
Jan 28, 2014·The Science of the Total Environment·Sophia S KonstantopoulouPolyxeni Nicolopoulou-Stamati
Oct 1, 2015·Nucleic Acids Research·Sara Ortega-AtienzaAnatoly Zhitkovich
Dec 10, 2009·The Lancet Oncology·Robert BaanUNKNOWN WHO International Agency for Research on Cancer Monograph Working Group
Jun 22, 2013·American Journal of Industrial Medicine·Laura E Beane FreemanMichael Hauptmann
Jun 22, 2013·American Journal of Industrial Medicine·Alysha R MeyersMisty J Hein
Apr 12, 2011·Histopathology·Patricia J T A GroenenJohan H J M van Krieken
Jan 26, 2011·Anatomical Sciences Education·Stephen M Duray, Craig L Mekow
Feb 7, 2014·American Journal of Industrial Medicine·Joseph K McLaughlin, Robert E Tarone
Jan 1, 2015·Annals of Occupational and Environmental Medicine·Pil Kyun JungJaehoon Roh
Dec 18, 2013·Journal of the American Academy of Dermatology·Mbulelo H ManeliNonhlanhla P Khumalo
Sep 29, 2015·Critical Reviews in Toxicology·Kenneth T Bogen, Jacqueline M Heilman
Apr 2, 2013·The Science of the Total Environment·Dinesh JohnPatty Freedson
Sep 23, 2014·The Journal of Toxicological Sciences·Tingzhu Teresa Meng
Sep 5, 2014·Journal of the Air & Waste Management Association·Steven Sai Hang HoLegolas Baggio Ho
May 23, 2016·Archives of Toxicology·Gunnar Damgård NielsenPeder Wolkoff
Sep 30, 2016·Critical Reviews in Toxicology·Richard J Albertini, Debra A Kaden
Sep 24, 2016·Analytical Chemistry·Yonghe TangWeiying Lin
Dec 8, 2016·Biomarkers in Medicine·Pieranna ChiarellaDamiano Carbonari
May 2, 2017·American Journal of Epidemiology·Briony MurphyFlavia Cicuttini
Jun 24, 2017·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·María SerranoManuel Silva
Dec 18, 2013·International Journal of Toxicology·Ivan J BoyerF Alan Andersen
Mar 30, 2017·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·William D Troutt, Matthew D DiDonato

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Luoping ZhangQing Lan
© 2022 Meta ULC. All rights reserved