PMID: 2496248Mar 1, 1989Paper

Mortality in patients on home parenteral nutrition

JPEN. Journal of Parenteral and Enteral Nutrition
M A Stokes, M H Irving

Abstract

Fifty out of 228 patients recorded on the U.K. Home Parenteral Nutrition Register have died. The earliest to die was at 10 days following the commencement of home parenteral nutrition (HPN), and the longest to die was after 5 1/2 years. Half of the patients who died, did so within 6 months of commencing HPN. Sixty % died of their underlying disease. Most patients with scleroderma or an underlying malignancy are dead within a year of commencing HPN. In contrast, patients with Crohn's disease or the short bowel syndrome due to volvulus do well. In only 14 patients was death attributable to the administration of HPN. In this group the main causes were septicemia, SVC thrombosis, and hepatic failure. Our study suggests that HPN should be used in patients with malignancy and scleroderma only in exceptional circumstances and that further work is necessary for the prevention of SVC thrombosis.

References

Aug 1, 1976·American Journal of Surgery·R A Sanders, G F Sheldon
Aug 16, 1986·Lancet·M Mughal, M Irving
Jan 1, 1985·JPEN. Journal of Parenteral and Enteral Nutrition·N L SmithS A Khan
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Citations

Jun 1, 1988·Diseases of the Colon and Rectum·M A Stokes, M H Irving
Feb 1, 1994·Irish Journal of Medical Science·M A Stokes, T F Gorey
Jan 1, 1992·Archives of Disease in Childhood·W M BissetP J Milla
Oct 1, 1992·Annals of the Rheumatic Diseases·A C LundbergB Akesson
Jul 14, 2006·Gut·J NightingaleUNKNOWN Small Bowel and Nutrition Committee of the British Society of Gastroenterology
Nov 16, 2007·Acta Veterinaria Scandinavica·Anna H EdnerBirgitta Essén-Gustavsson
Apr 1, 1992·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·E NäslundL Backman
Aug 14, 2010·La Revue de médecine interne·D LebeauxB Fantin
Jun 1, 1995·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·C R Pennington
Jun 1, 1991·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·C R Pennington
Dec 1, 1992·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·T O'hanrahan, M H Irving
Apr 9, 2001·Clinics in Liver Disease·I S SandhuG T Everson
Jun 16, 2001·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·A Van GossumUNKNOWN ESPEN-HAN Working Group
Jun 28, 2007·JPEN. Journal of Parenteral and Enteral Nutrition·Ming-Yang WangMing-Tsan Lin
Jun 1, 1995·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·B Messing
Apr 1, 1990·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·R S HurleyC Murphy
Sep 1, 1990·JPEN. Journal of Parenteral and Enteral Nutrition·T R BeersC R Fleming
Jul 1, 1992·The British Journal of Surgery·C L Ingham ClarkR F Wood
May 1, 1992·The British Journal of Surgery·M A Stokes
Sep 2, 1992·Journal of Wound Care·S M G McLaren
Jun 1, 1992·Scottish Medical Journal·C R Pennington

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